Results 51 to 60 of about 178,592 (262)

Proteomic Analysis of Circulating Immune Complexes from Tuberculosis Patients

Journal of Pure and Applied Microbiology, 2019
Circulating immune complexes (CIC’s) are associated with disease progression in Tuberculosis (TB) though their role in pathogenesis is still unclear. Hence the present study was undertaken to identify proteins of diagnostic potential in tuberculosis by
Ajay Kumar, Kiran Chawla, Rupesh Thakur, Manjunath B. Joshi, Kapaettu Satyamoorthy, Dakshina Bisht   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

C-PRISM: Complexity-informed profile for research impact and scholarly merit

Journal of Family Medicine and Primary Care
A BSTRACT The h-index, despite widespread adoption, inadequately captures the multidimensional nature of scholarly contribution, conflating productivity with impact while ignoring leadership, independence, research integrity, and collaboration quality.
Raina, Sunil Kumar, Kumar, Raman, Kaushal, Kanica   +2 more
openaire   +2 more sources

Exhuming an Accretionary Prism: A Case Study of the Kodiak Accretionary Complex, Alaska, USA

Tectonics, 2023
AbstractWe have carried a structural study across Kodiak accretionary complex in Alaska, USA, in order to describe its thermal structure and decipher the processes of exhumation. The accretionary complex consists of a stack of tectonic mélanges and coherent units. Mélanges are characterized by simple shear deformation with a pervasive network of top‐to‐
Rajič, Kristijan, Raimbourg, Hugues, Famin, Vincent, Moris‐muttoni, Benjamin, Fisher, Donald, Morell, Kristin, Canizarés, Aurélien   +6 more
openaire   +4 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

BIURET COMPLEXES OF PRASEODYMIUM AND HOLMIUM BROMIDES

Тонкие химические технологии, 2013
We present the synthesis of new complexes of praseodymium and holmium bromides and biuret (NH2CONHCONH₂ - BU), PrBr₃2BU4H₂O (I) и HoBr₃2BU4H<sub>2< ...
L. Yu. Alikberova, T. A. Antonenko, D. V. Albov, G. A. Fedorova, M. G. Zaitseva, E. V. Volchkova   +5 more
doaj  

Mobility-as-a-Service (MaaS) and sustainable urban mobility in the development of the European museum business: a case study of Spain [PDF]

E3S Web of Conferences
The purpose of this article is to analyze the current state of museums in Spain through the prism of the dynamic development of innovative technologies in society.
Tsypko Victoria, Shcherbakova Nadiia, Riaboshtan Liudmyla   +2 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Representations about an ideal citizen during the crisis of the Roman Republic using the example of Cato the Elder

Ученые записки Казанского университета: Серия Гуманитарные науки, 2020
The problem of Roman civic values was considered through the prism of the ideal citizen image. The moral relativism of the Roman society was noted: the hard-edged boundaries of what is allowed are deterred by the authority of an ideal citizen.
A.O. Kudratov
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source