Results 151 to 160 of about 8,519 (204)

MTAP Deficiency as a Metabolic Vulnerability in Cancer: Implications for Synthetic Lethal Therapy. [PDF]

Cancer Sci
Ikushima H, Kage H.
europepmc   +1 more source

Identification of METTL3 and PRMT5 as an oncogenic pair for the prognosis and therapeutic targets of colorectal cancer subtype. [PDF]

Clin Epigenetics
Zhao Q, Li S, Chen A, Zhu S, Zhong J, Zhang P, She YL, Chen R, Liu W, Wang Y.   +9 more
europepmc   +1 more source

PRMT5-mediated intron retention triggers innate and adaptive immunity against cancer. [PDF]

EMBO Mol Med
Blaszczak W, Barczak W, Zhang C, Rochford G, Nicastri A, Hutchings C, Samsonova A, Kanapin A, Ternette N, Klenerman P, La Thangue NB.   +10 more
europepmc   +1 more source

Inhibition of PRMT5 reduces angiogenesis in a corneal neovascularization model by blocking NLRP3-mediated pyroptosis. [PDF]

Clin Epigenetics
Mao J, Ding S, Deng Q, Yang Z, Shi X, Wang Y, Yang W, Yang Y, Wan S.   +8 more
europepmc   +1 more source

Exploring the BICC1 Interactome in HEK293T Cells: Insights Into RNA-Mediated Protein Networks and Biomolecular Condensates. [PDF]

FASEB Bioadv
do Amaral-Prado HM, Moreira GA, Santos C, Bosso FH, Ciamponi FE, Barbosa GO, Bengtson MH, Massirer KB.   +7 more
europepmc   +1 more source

Structure-Guided Discovery of Novel Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitors. [PDF]

ACS Med Chem Lett
Huang C, Liang M, Zhang P, Liu G, Liao C.   +4 more
europepmc   +1 more source

Affinity purification contaminants identified by cryo-EM and mass spectrometry. [PDF]

Biosci Rep
Belcher ER, Hardwick SW, Maia de Oliveira T, Hyvönen M.   +3 more
europepmc   +1 more source

The detection of MTAP loss in non-small cell lung cancer: a novel biomarker with therapeutic implications. [PDF]

Transl Lung Cancer Res
Choi E, Koorapati G, Kumar PA.
europepmc   +1 more source

Quantitative Global Proteomics of Formalin-Fixed Paraffin-Embedded Tumors Identifies Dimethylated G3BP1 at Arginine 460 as a Robust Pharmacodynamic Biomarker of Methylthioadenosine Phosphorylase-Selective Protein Arginine Methyltransferase 5 Inhibition. [PDF]

J Proteome Res
Tu A, Wiseman EJ, Sweet SM, Urosevic J, Loizou J, Barnicle A, Richardson C, Abhishek S, Chain DC, Kim YJ, Chambers AG.   +10 more
europepmc   +1 more source

PCK2-Mediated PQBP1 Lactylation Promotes Asthmatic Inflammation through PRMT5 Inhibition. [PDF]

Research (Wash D C)
Bai Q, Ding N, Feng R, Shang F, Wang Z, Li L, Wang Z, Piao Y, Wang C, Song Y, Yan G.   +10 more
europepmc   +1 more source