Aflibercept 5+PRN with retinal laser photocoagulation is more effective than retinal laser photocoagulation alone and aflibercept 3+PRN with retinal laser photocoagulation in patients with high-risk proliferative diabetic retinopathy and diabetic macular edema: a 12-month clinical trial [PDF]
ObjectiveThis study aimed to investigate and compare the efficacy and safety of retinal laser photocoagulation (PRP) alone, PRP with aflibercept 3+PRN, and PRP with aflibercept 5+PRN in patients with both high-risk proliferative diabetic retinopathy (PDR)
Shuting Li +6 more
doaj +2 more sources
RX: PROFESSIONAL INTEGRITY (PRN)
David S David
openalex +4 more sources
Ophthalmic community perception of new medication needs [PDF]
AIM: To survey ophthalmologists (who have participated previously in clinical research) and ophthalmic industry professionals (who have been involved in ocular research and development) to indicate perceived needs for new pharmaceuticals in various ...
William C. Stewart +2 more
doaj +1 more source
Respiratory infections caused by Bordetella pertussis are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating B.
Michiel M. Kroes +11 more
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Prevalence and genetic characterization of pertactin-deficient Bordetella pertussis in Japan. [PDF]
The adhesin pertactin (Prn) is one of the major virulence factors of Bordetella pertussis, the etiological agent of whooping cough. However, a significant prevalence of Prn-deficient (Prn(-)) B. pertussis was observed in Japan.
Nao Otsuka +6 more
doaj +1 more source
Konflik berkepanjangan yang terjadi di Afghanistan telah menghancurkan kehidupan masyarakat terutama, kaum perempuan dan anak. Tidak sedikit upaya telah dilakukan oleh pemerintah Afghanistan untuk menyelesaikan konflik demi menciptakan perdamaian.
Arief Rachman MD +5 more
doaj +1 more source
Comparison of one and three initial monthly intravitreal ranibizumab injection in patients with macular edema secondary to branch retinal vein occlusion [PDF]
AIM: To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO).
Alper Halil Bayat +5 more
doaj +1 more source
Comparison of two different treatment regimens’ efficacy in neovascular age-related macular degeneration in Turkish population—based on real life data-Bosphorus RWE Study Group [PDF]
AIM: To compare two different anti-vascular endothelial growth factor (anti-VEGF) treatment regimens’-a priori pro re nata (PRN) and PRN regimen following the loading phase-anatomical and functional results in neovascular age-related macular degeneration
Burak Erden +16 more
doaj +1 more source

