Results 21 to 30 of about 85,448 (212)

Functionalized Lipid Nanocarriers for Simultaneous Delivery of Docetaxel and Tariquidar to Chemoresistant Cancer Cells

open access: yesPharmaceuticals, 2023
The simultaneous drug delivery efficiency of a co-loaded single-carrier system of docetaxel (DTX)- and tariquidar (TRQ)-loaded nanostructured lipid carrier (NLC) functionalized with PEG and RIPL peptide (PRN) (D^T-PRN) was compared with that of a ...
Chang Hyun Kim   +7 more
doaj   +1 more source

Polyyne Ring Nucleus Growth Model for Single-Layer Carbon Nanotubes [PDF]

open access: yes, 1996
We propose, based on recent experimental results, a polyyne ring nucleus (PRN) growth model for the synthesis of single-layer nanotubes (SLN's). The PRN model assumes that (i) the critical nuclei are the planar carbon polyyne rings that are observed to ...
Goddard, William A, III   +1 more
core   +2 more sources

Engineering of hybrid anticancer drug-loaded polymeric nanoparticles delivery system for the treatment and care of lung cancer therapy

open access: yesDrug Delivery, 2021
Chemotherapy with combination drugs has become one of the most commonly used cancer prevention treatments, with positive clinical results. The goal of this study was to develop compostable polymeric nanomaterials (NMs) for the delivery of puerarin (PRN ...
Yang Zhao   +4 more
doaj   +1 more source

Challenges in the End-of-Life Care for Patients With Severe Persistent Mental Illness: A Case Series. [PDF]

open access: yesPsychogeriatrics
ABSTRACT Introduction Despite reduced life expectancy and high rates of comorbidity, individuals with severe persistent mental illness (SPMI) face significant disparities in healthcare access and quality, which extends to palliative and end‐of‐life (EOL) care.
Jayakody K, Bajaj I, Blomeley D.
europepmc   +2 more sources

Prevalence and characterization of pertactin deficient Bordetella pertussis strains in Brazil, a whole-cell vaccine country

open access: yesVaccine: X, 2021
Many countries have reported antigenic divergence among circulating Bordetella pertussis strains, mainly in those countries which introduced the acellular pertussis (aP) vaccine. This phenomenon can be seen, for example, with the recent rise of pertactin
Daniela Leite   +9 more
doaj   +1 more source

Continuing posterior tibial nerve stimulation after twelve weekly sessions: a randomized controlled trial

open access: yesUrogynaecologia International Journal, 2022
Posterior Tibial Nerve Stimulation (PTNS) is a treatment option for refractory Overactive Bladder (OAB). There is currently no evidence to support which maintenance schedule is most effective.
Jessica S. Zigman   +6 more
doaj   +1 more source

Pharmacoeconomic analysis of anti-VEGF therapy for age-related macular degeneration

open access: yesКачественная клиническая практика, 2018
Diabetes mellitus (DM) is a widespread, severe disease that has outpaced many infectious and non-infectious diseases in terms of both incidence increases and economic burden in most developed countries.
A. E. Cheberda   +2 more
doaj   +1 more source

Bordetella pertussis pertactin knock-out strains reveal immunomodulatory properties of this virulence factor. [PDF]

open access: yes, 2018
Whooping cough, caused by Bordetella pertussis, has resurged and presents a global health burden worldwide. B. pertussis strains unable to produce the acellular pertussis vaccine component pertactin (Prn), have been emerging and in some countries ...
Hamstra, Hendrik-Jan   +9 more
core   +4 more sources

Pharmacoeconomic analysis of ranibizumab and aflibercept for treatment of diabetic macular edema

open access: yesКачественная клиническая практика, 2018
Diabetes mellitus (DM) is a widespread, severe disease that has outpaced many infectious and non-infectious diseases in terms of both incidence increases and economic burden in most developed countries.
A. E. Cheberda   +2 more
doaj   +1 more source

Staff perceptions of PRN medication in a residential care setting [PDF]

open access: yes, 2019
Purpose- The aim was to explore the perceptions of staff towards psychotropic Pro Re Nata (PRN) medication in a residential care setting. Design- Three male and seven female participants were interviewed using a semi-structured interview.
Hughes, Kyle   +2 more
core   +1 more source

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