Results 1 to 10 of about 85,448 (212)

Pathogenicity and vaccine protection of circulating pertactin- and filamentous hemagglutinin-deficient Bordetella pertussis strains [PDF]

Emerging Microbes and Infections
The increasing emergence of vaccine antigen-deficient Bordetella pertussis (Bp) variants has raised concerns regarding disease control and prevention. Here, we characterized the pathogenicity and vaccine protection of circulating pertactin-deficient (PRN−
Hanying Dai, Xiuwen Sui, Jie Che, Chunying Zhang, Jiayu Zhao, Jie Li, Bohan Chen, Luyao Guo, Dongshan Yan, Hairui Wang, Xueping Liu, Li Xu, Yuan Gao, Aiping Qin, Tao Zhu, Maojun Zhang, Zhujun Shao   +16 more
doaj   +2 more sources

Comparative study on the efficacy of different aflibercept regimens in the treatment of macular edema secondary to branch retinal vein occlusion [PDF]

Frontiers in Medicine
ObjectivesTo compare the efficacy of intravitreal injection of aflibercept between the treat-and-extend (TAE) and pro re nata (PRN, as needed) regimens in the treatment of macular edema secondary to branch retinal vein occlusion, to determine the best ...
Xing Du, Yuanyuan Guo, Min Du, Wen Wang, Mingkun Liu, Shanshan Li, Yanjuan Sheng   +6 more
doaj   +2 more sources

Prevalence and types of medication errors in pro re nata medication orders among hospitalized patients: a cross-sectional study [PDF]

Journal of Pharmaceutical Health Care and Sciences
Background Medication errors in Pro Re Nata (PRN) prescriptions pose a significant threat in hospital settings, especially due to unclear prescribing practices.
Arefeh Rasouli-Rad, Mahdi Ahmadinia, Azadeh Eshraghi, Hamidreza Aslani, Zahra Karimian, Akram Hashemi, Maryam Farasatinasab   +6 more
doaj   +2 more sources

Ophthalmic community perception of new medication needs [PDF]

International Journal of Ophthalmology, 2018
AIM: To survey ophthalmologists (who have participated previously in clinical research) and ophthalmic industry professionals (who have been involved in ocular research and development) to indicate perceived needs for new pharmaceuticals in various ...
William C. Stewart, Jeanette A. Stewart, Lindsay A. Nelson   +2 more
doaj   +1 more source

Naturally circulating pertactin-deficient Bordetella pertussis strains induce distinct gene expression and inflammatory signatures in human dendritic cells

Emerging Microbes and Infections, 2021
Respiratory infections caused by Bordetella pertussis are reemerging despite high pertussis vaccination coverage. Since the introduction of the acellular pertussis vaccine in the late twentieth century, circulating B.
Michiel M. Kroes, Alberto Miranda-Bedate, Elise S. Hovingh, Ronald Jacobi, Corrie Schot, Elder Pupo, René H. M. Raeven, Arno A. J. van der Ark, Jos P. M. van Putten, Jelle de Wit, Rob Mariman, Elena Pinelli   +11 more
doaj   +1 more source

Prevalence and genetic characterization of pertactin-deficient Bordetella pertussis in Japan. [PDF]

PLoS ONE, 2012
The adhesin pertactin (Prn) is one of the major virulence factors of Bordetella pertussis, the etiological agent of whooping cough. However, a significant prevalence of Prn-deficient (Prn(-)) B. pertussis was observed in Japan.
Nao Otsuka, Hyun-Ja Han, Hiromi Toyoizumi-Ajisaka, Yukitsugu Nakamura, Yoshichika Arakawa, Keigo Shibayama, Kazunari Kamachi   +6 more
doaj   +1 more source

DIPLOMASI INDONESIA DALAM MEMPERKUAT KOMITMEN PEMBERDAYAAN PEREMPUAN UNTUK MENDUKUNG PROSES PERDAMAIAN AFGHANISTAN

Jurnal Ilmiah Hubungan Internasional, 2020
Konflik berkepanjangan yang terjadi di Afghanistan telah menghancurkan kehidupan masyarakat terutama, kaum perempuan dan anak. Tidak sedikit upaya telah dilakukan oleh pemerintah Afghanistan untuk menyelesaikan konflik demi menciptakan perdamaian.
Arief Rachman MD, Marissa Aulia, Nigin Abdulrab, Yulius Purwadi, Mia Dayanti Fajar, A.A.S. Dyah Ayunda   +5 more
doaj   +1 more source

Comparison of one and three initial monthly intravitreal ranibizumab injection in patients with macular edema secondary to branch retinal vein occlusion [PDF]

International Journal of Ophthalmology, 2018
AIM: To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO).
Alper Halil Bayat, Akın Çakır, Şeyma Gülcenur Özturan, Selim Bölükbaşı, Burak Erden, Mustafa Nuri Elçioğlu   +5 more
doaj   +1 more source

Comparison of two different treatment regimens’ efficacy in neovascular age-related macular degeneration in Turkish population—based on real life data-Bosphorus RWE Study Group [PDF]

International Journal of Ophthalmology, 2020
AIM: To compare two different anti-vascular endothelial growth factor (anti-VEGF) treatment regimens’-a priori pro re nata (PRN) and PRN regimen following the loading phase-anatomical and functional results in neovascular age-related macular degeneration
Burak Erden, Selim Bölükbaşı, Abdullah Özkaya, Levent Karabaş, Cengiz Alagöz, Zeynep Alkın, Özgür Artunay, Sadık Etka Bayramoğlu, Gökhan Demir, Mehmet Demir, Ali Demircan, Gürkan Erdoğan, Mehmet Erdoğan, Erdem Eriş, Havva Kaldırım, İsmail Umut Onur, Özen Ayrancı Osmanbaşoğlu   +16 more
doaj   +1 more source

Comparisons of One to Three Monthly Injections of Aflibercept for Diabetic Macular Edema by Practical Protocol

Journal of Diabetes Research, 2021
The purpose of this study was to compare the efficacies of one initial intravitreal injection of aflibercept followed by a pro re nata (PRN; 1+PRN) regimen to those of three consecutive monthly injections followed by the PRN (3+PRN) regimen for diabetic ...
Yuko Hayashi, Tomoaki Tatsumi, Toshiyuki Oshitari, Tomomi Kaiho, Yoko Takatsuna, Miyuki Arai, Takayuki Baba, Shuichi Yamamoto   +7 more
doaj   +1 more source