Results 101 to 110 of about 22,531,219 (286)
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
A Probabilistic Quantitative Analysis of Probabilistic-Write/Copy-Select
, 2013 Probabilistic-Write/Copy-Select (PWCS) is a novel synchronization scheme suggested by Nicholas Mc Guire which avoids expensive atomic operations for synchronizing access to shared objects. Instead, PWCS makes inconsistencies detectable and recoverable. It builds on the assumption that, for typical workloads, the probability for data races is very small.
Christel Baier +5 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
On the limits of probabilistic timing analysis
, 2023 Over the last years, we are witnessing the steady and rapid growth of Critica! Real-Time Embedded Systems (CRTES) industries, such as automotive and aerospace. Many of the increasingly-complex CRTES' functionalities that are currently implemented with mechanical means are moving towards to an electromechanical implementation controlled by critica ...
openaire +4 more sources
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Bioscience Journal, 2017 The economic viability of feedlot Aberdeen Angus steers fed with diets composed of different concentrate levels (CL) in dry matter (25, 40, 55 or 70%) was estimated using Monte Carlo simulation combined with Spearman rank correlation, considering nine ...
Joilmaro Rodrigo Pereira Rosa +4 more
doaj
A probabilistic analysis on general probabilistic scheduling problems
2024 IEEE International Symposium on Information Theory (ISIT)15 ...
openaire +4 more sources
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Financial Markets Analysis by Probabilistic Fuzzy Modelling [PDF]
For successful trading in financial markets, it is important to develop financial models where one can identify different states of the market for modifying one???s actions.
Berg, J. van den +2 more
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