Results 101 to 110 of about 890,561 (342)
Formulation of an optimal academic exam
Journal of Computer Science and Technology, 2018 The aim of this paper is to formulate an optimal academic exam for a given subject. To do this, the probability is first modelled of a student passing the exam according to the number of units he studies and the professor evaluates. That simulation model
Enrique E. Tarifa +3 more
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FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Bayesian Probabilistic Reasoning Applied to Mathematical Epidemiology for Predictive Spatiotemporal Analysis of Infectious Diseases [PDF]
, 2006 Abbas, Kaja Moinudeen
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FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The rogue nature of hiatuses in a global warming climate
Geophysical Research Letters, 2016 The nature of rogue events is their unlikelihood and the recent unpredicted decade‐long slowdown in surface warming, the so‐called hiatus, may be such an event.
F. Sévellec, B. Sinha, N. Skliris
doaj +1 more source
A Probabilistic Analysis of Causation [PDF]
The British Journal for the Philosophy of Science, 2011 The starting point in the development of probabilistic analyses of token causation has usually been the naive intuition that, in some relevant sense, a cause raises the probability of its effect. But there are well-known examples both of non-probability-raising causation and of probability-raising non-causation.
openaire +4 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source