Results 101 to 110 of about 164,916 (266)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

On the limits of probabilistic timing analysis

open access: yes, 2023
Over the last years, we are witnessing the steady and rapid growth of Critica! Real-Time Embedded Systems (CRTES) industries, such as automotive and aerospace. Many of the increasingly-complex CRTES' functionalities that are currently implemented with mechanical means are moving towards to an electromechanical implementation controlled by critica ...
openaire   +4 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Risk analysis of the economic viability of feedlot aberdeen angus steers fed with different proportions of concentrate

open access: yesBioscience Journal, 2017
The economic viability of feedlot Aberdeen Angus steers fed with diets composed of different concentrate levels (CL) in dry matter (25, 40, 55 or 70%) was estimated using Monte Carlo simulation combined with Spearman rank correlation, considering nine ...
Joilmaro Rodrigo Pereira Rosa   +4 more
doaj  

A probabilistic analysis on general probabilistic scheduling problems

open access: yes2024 IEEE International Symposium on Information Theory (ISIT)
15 ...
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

The rogue nature of hiatuses in a global warming climate

open access: yesGeophysical Research Letters, 2016
The nature of rogue events is their unlikelihood and the recent unpredicted decade‐long slowdown in surface warming, the so‐called hiatus, may be such an event.
F. Sévellec, B. Sinha, N. Skliris
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Probabilistic Analysis of Simpson′s Quadrature

open access: yesJournal of Complexity, 1994
The author studies the probabilistic properties of Simpson's quadrature rule, by assuming that the integrand is equipped with a variant of the \(r\)-fold Wiener measure. In the average settting he shows that the error is minimal when one uses equally spaced nodes. He proves that the composite Simpson's rule using such points is almost optimal among all
openaire   +1 more source

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