Results 91 to 100 of about 164,916 (266)
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Probabilistic Semantics and Program Analysis [PDF]
, 2010 The aims of these lecture notes are two-fold: (i) we investigate the relation between the operational semantics of probabilistic programming languages and Discrete Time Markov Chains (DTMCs), and (ii) we present a framework for probabilistic program analysis which is inspired by the classical Abstract Interpretation framework by Cousot & Cousot and ...
Alessandra Di Pierro +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
On Quantitative Analysis of Probabilistic Protocols
Electronic Notes in Theoretical Computer Science, 2005 AbstractWe advocate the use of approximate noninterference for the security analysis of probabilistic protocols. Our approach relies on a formalisation of the protocol in the setting of a probabilistic process algebra and a notion of process similarity based on weak probabilistic bisimulation. We illustrate this approach by presenting the analysis of a
Alessandro Aldini, Alessandra Di Pierro
openaire +3 more sources
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Formulation of an optimal academic exam
Journal of Computer Science and Technology, 2018 The aim of this paper is to formulate an optimal academic exam for a given subject. To do this, the probability is first modelled of a student passing the exam according to the number of units he studies and the professor evaluates. That simulation model
Enrique E. Tarifa +3 more
doaj +1 more source
A Probabilistic Quantitative Analysis of Probabilistic-Write/Copy-Select
, 2013 Probabilistic-Write/Copy-Select (PWCS) is a novel synchronization scheme suggested by Nicholas Mc Guire which avoids expensive atomic operations for synchronizing access to shared objects. Instead, PWCS makes inconsistencies detectable and recoverable. It builds on the assumption that, for typical workloads, the probability for data races is very small.
Christel Baier +5 more
openaire +3 more sources