Results 71 to 80 of about 22,531,219 (286)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Verification tools for probabilistic forecasts of continuous hydrological variables [PDF]

open access: yes, 2006
In the present paper we describe some methods for verifying and evaluating probabilistic forecasts of hydrological variables. We propose an extension to continuous-valued variables of a verification method originated in the meteorological literature for ...
Tamea, Stefania   +5 more
core   +2 more sources

Análise probabilística do concreto reforçado com fibras utilizado na construção do dique seco do Estaleiro Rio Grande

open access: yesRevista IBRACON de Estruturas e Materiais
A variabilidade da resistência do concreto torna fundamental a utilização de metodologias estatísticas capazes de estabelecer parâmetros para a aceitação das estruturas.
F. C. Magalhães, M. V. Real
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Random finite element analysis on ground subsidence caused by tunnel excavation in karst regions with spatial variable soil

open access: yesDeep Underground Science and Engineering
The construction of tunnels inevitably leads to ground subsidence, while surface collapses caused by caverns during excavation can result in significant financial losses.
Zhenghong Su   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Event‐Level Linkages Between Atmospheric Circulation and Anomalous Precipitation Types in a Typical East Asian Monsoon Basin

open access: yesGeophysical Research Letters
Anomalous precipitation, with unexpected intensity and/or spatiotemporal structures, makes flood risk management in the East Asian monsoon regions challenging, where interacting circulation systems generate highly variable precipitation events.
Wenpeng Zhao   +8 more
doaj   +1 more source

Deterministic and Probabilistic Assessment of Failure Mechanisms in Geosynthetic-Reinforced Embankments

open access: yesApplied Sciences
Geosynthetic-reinforced embankments are subject to two primary failure mechanisms: bond failure and rupture. Bond failure occurs when the critical slip surface extends beyond the reinforced zone, while rupture occurs when the slip surface intersects the ...
Shen Zhang   +6 more
doaj   +1 more source

Incorporating the effect of ALS-derived DEM uncertainty for quantifying changes due to the landslide in 2011, Mt. Umyeon, Seoul

open access: yesGIScience & Remote Sensing, 2020
The landslide, which occurred at Umyeon mountain (Mt. Umyeon) in Seoul, Korea in 2011, was a prime example that raised awareness about the landslide in the highly urbanized area.
Mi-Kyeong Kim   +2 more
doaj   +1 more source

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