Results 51 to 60 of about 890,561 (342)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Analysis of Non-Linear Probabilistic Hybrid Systems

, 2011
This paper shows how to compute, for probabilistic hybrid systems, the clock approximation and linear phase-portrait approximation that have been proposed for non probabilistic processes by Henzinger et al.
Assouramou, Joseph, Desharnais, Josée
core   +2 more sources

Identification and separation of DNA mixtures using peak area information [PDF]

, 2004
We introduce a new methodology, based upon probabilistic expert systems, for analysing forensic identification problems involving DNA mixture traces using quantitative peak area information.
Cowell, R., Lauritzen, S. L., Mortera, J.   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Probabilistic analysis of concrete beams during fire [PDF]

, 2011
In this paper a simple computational tool is presented, which provides insight in the time and temperature dependent reliability of concrete beams during fire.
Annerel, Emmanuel, Caspeele, Robby, Taerwe, Luc, Van Coile, Ruben   +3 more
core  

Evaluating probabilistic programming languages for simulating quantum correlations

, 2018
This article explores how probabilistic programming can be used to simulate quantum correlations in an EPR experimental setting. Probabilistic programs are based on standard probability which cannot produce quantum correlations.
Bruza, Peter D., Obeid, Abdul, Wittek, Peter   +2 more
core   +1 more source

Manifold Hypothesis in Data Analysis: Double Geometrically-Probabilistic Approach to Manifold Dimension Estimation [PDF]

, 2021
Alexander Ivanov, Gleb V. Nosovskiy, Alexey Chekunov, D. A. Fedoseev, В. А. Кибкало, Mikhaïl Nikulin, Fedor Popelenskiy, Stepan Komkov, I. L. Mazurenko, Aleksandr Petiushko   +9 more
openalex   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Parameterized Reduced-Order Models for Probabilistic Analysis of Thermal Protection System Based on Proper Orthogonal Decomposition

Aerospace
The thermal protection system (TPS) represents one of the most critical subsystems for vehicle re-entry. However, due to uncertainties in thermal loads, material properties, and manufacturing deviations, the thermal response of the TPS exhibits ...
Kun Zhang, Jianyao Yao, Wenxiang Zhu, Zhifu Cao, Teng Li, Jianqiang Xin   +5 more
doaj   +1 more source

Quicksort with unreliable comparisons: a probabilistic analysis

, 2003
We provide a probabilistic analysis of the output of Quicksort when comparisons can err.Comment: 29 pages, 3 ...
Alonso, L., Chassaing, P., Gillet, F., Janson, S., Reingold, E. M., Schott, R.   +5 more
core   +4 more sources