Results 61 to 70 of about 33,963 (308)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Theory-independent randomness generation from spatial symmetries [PDF]
QuantumWe demonstrate a fundamental relation between the structures of physical space and of quantum theory: the set of quantum correlations in a rotational prepare-and-measure scenario can be derived from covariance alone, without assuming quantum physics.
Caroline L. Jones +3 more
doaj +1 more source
Hausdorff measure of arcs and Brownian motion on Brownian spatial trees [PDF]
, 2009 A Brownian spatial tree is defined to be a pair $(\mathcal{T},\phi)$, where $\mathcal{T}$ is the rooted real tree naturally associated with a Brownian excursion and φ is a random continuous function from $\mathcal{T}$ into ℝd such that, conditional on ...
Croydon, David A.
core +1 more source
Axioms, 2023 In this article, we give the sharp bounds of probabilistic Kolmogorov N,δ-widths and probabilistic linear N,δ-widths of the multivariate Sobolev space W2A with common smoothness on a Sq norm equipped with the Gaussian measure μ, where A⊂Rd is a finite ...
Yuqi Liu, Xuehua Li, Huan Li
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Generic Infinite Traces and Path-Based Coalgebraic Temporal Logics
, 2010 This paper gives a general coalgebraic account of the notions of possibly infinite trace and possibly infinite execution in state-based, dynamical systems, by extending the generic theory of finite traces and executions developed by Hasuo and coauthors ...
Cirstea, Corina, Corina Cîrstea
core +1 more source
A Weighted Evidence Combination Approach for Target Identification in Wireless Sensor Networks
IEEE Access, 2017 Information fusion using evidence theory in wireless sensors networks has been used extensively to identify targets because it offers the advantage of handling uncertainty. But the classical Dempster's combination rule cannot deal with highly conflicting
Yang Zhang +5 more
doaj +1 more source
Natural information measures in Cox' approach for contextual probabilistic theories
, 2015 Fil: Holik, Federico Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas.
Holik, F., A, Plastino, Sáenz, M.
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source