Results 101 to 110 of about 14,817,250 (289)
Deep Probabilistic Graphical Modeling
CoRR, 2020 Probabilistic graphical modeling (PGM) provides a framework for formulating an interpretable generative process of data and expressing uncertainty about unknowns, but it lacks flexibility. Deep learning (DL) is an alternative framework for learning from data that has achieved great empirical success in recent years.
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
工程科学与技术, 2013 :In order to study the deteriorating mechanism of the structure performance, the resistance of deteriorating structures was described by Gamma distribution which has a character of independent increment, the changing process of load was described by ...
张社荣, 王超, 孙博
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A review of probabilistic analysis in orthopaedic biomechanics
, 2010 Probabilistic analysis methods are being increasingly applied in the orthopaedics and biomechanics literature to account for uncertainty and variability in subject geometries, properties of various structures, kinematics and joint loading, as well as ...
Laz, P. J. +3 more
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Наука и техника, 2019 Reinforcement corrosion of marine and coastal hydraulic structures due to chloride aggression and concrete carbonization leads to a sharp decrease in structure safety.
S. N. Leonovich, E. E. Shalyi, L. V. Kim
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
The Libra Toolkit for Probabilistic Models
J. Mach. Learn. Res., 2015 The Libra Toolkit is a collection of algorithms for learning and inference with discrete probabilistic models, including Bayesian networks, Markov networks, dependency networks, and sum-product networks. Compared to other toolkits, Libra places a greater emphasis on learning the structure of tractable models in which exact inference is efficient.
Daniel Lowd, Amirmohammad Rooshenas
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Applied SciencesPavement infrastructure deteriorates progressively under the combined influence of multiple uncertainty-related factors making accurate deterioration prediction essential for effective Pavement Management Systems (PMSs).
Theodora Vagdatli +1 more
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