Results 71 to 80 of about 14,817,250 (289)

Probabilistic Graphical Models [PDF]

, 2014
This report presents probabilistic graphical models that are based on imprecise probabilities using a simplified language. In particular the discussion is focused on credal networks and discrete domains. It describes the building blocks of credal networks algorithms to perform inference and discusses on complexity results and related work.
Antonucci, Alessandro, de Campos, Cassio P., Zaffalon, Marco   +2 more
openaire   +1 more source

Comparative analysis of selected probabilistic customer lifetime value models in online shopping

Journal of Business Economics and Management, 2019
The selection of a suitable customer lifetime value (CLV) model is a key issue for companies that are introducing a CLV managerial approach in their online B2C relationship stores.
Pavel Jasek, Lenka Vrana, Lucie Sperkova, Zdenek Smutny, Marek Kobulsky   +4 more
doaj   +1 more source

Probabilistic Application of an Integrated Catchment-Estuary-Coastal System Model to Assess the Evolution of Inlet-Interrupted Coasts Over the 21st Century

Frontiers in Marine Science, 2020
Inlet-interrupted sandy coasts are dynamic and complex coastal systems with continuously evolving geomorphological behaviors under the influences of both climate change and human activities. These coastal systems are of great importance to society (e.g.,
Janaka Bamunawala, Janaka Bamunawala, Ali Dastgheib, Roshanka Ranasinghe, Roshanka Ranasinghe, Roshanka Ranasinghe, Ad van der Spek, Ad van der Spek, Shreedhar Maskey, A. Brad Murray, Patrick L. Barnard, Trang Minh Duong, Trang Minh Duong, Trang Minh Duong, T. A. J. G. Sirisena, T. A. J. G. Sirisena   +15 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Meta-probabilistic Modeling

CoRR
Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative trial-and-error. This challenge arises because classical PGMs typically operate on individual datasets. In this work, we
Kevin Zhang, Yixin Wang
openaire   +3 more sources

A Probabilistic Model of Oil Discovery [PDF]

The Review of Economics and Statistics, 1980
A probabilistic discovery model modified after Kaufman's earlier model is simplified to reduce computational demands and to reduce the sensitivity of the resulting estimates. The model is applied to the North Sea to estimate remaining oil reserves and forecast future discoveries.
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

On the expressiveness of probabilistic XML models [PDF]

The VLDB Journal, 2009
Various known models of probabilistic XML can be represented as instantiations of the abstract notion of p-documents. In addition to ordinary nodes, p-documents have distributional nodes that specify the possibleworlds and their probabilistic distribution.
Abiteboul, Serge, Kimelfeld, Benny, Sagiv, Y., Senellart, Pierre   +3 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source