Results 51 to 60 of about 360,925 (264)

Weighted scoringRules: Emphasizing Particular Outcomes When Evaluating Probabilistic Forecasts

Journal of Statistical Software
When predicting future events, it is common to issue forecasts that are probabilistic, in the form of probability distributions over the range of possible outcomes. Such forecasts can be evaluated using proper scoring rules.
Sam Allen
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Opinion dynamics with confirmation bias. [PDF]

PLoS ONE, 2014
Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one's preexisting beliefs. It is omnipresent in psychology, economics, and even scientific practices.
Armen E Allahverdyan, Aram Galstyan
doaj   +1 more source

Why are probabilistic laws governing quantum mechanics and neurobiology?

, 2004
We address the question: Why are dynamical laws governing in quantum mechanics and in neuroscience of probabilistic nature instead of being deterministic?
Abbot, Albert, Albert, Amit, Amit, Amit, Amit, Amit, Avelino, Bak, Bak, Barabasi, Barabasi, Battye, Benzi, Bliss, Bohland, Byrne, Coffins, Courant, Douglass, El Naschie, El Naschie, Ferster, Feynman, Grammaitoni, Grumbacher, Hebb, Helmut Kröger, Hertz, Hertz, Hopfield, Itzykson, James, Jeong, Kandel, Kleinberg, Kröger, Kröger, Lago-Fernandez, Laskar, Levin, Linsker, Longtin, Messiah, Metropolis, Moss, Murray, Nicholis, Noest, Nozaki, O’Dell, Peebles, Penrose, Rattay, Schuman, Squire, Strogatz, Sussman, Thompson, Tolhurst, von der Malsburg, von der Malsburg, Watts, Watts, Watts, Webb, Wiesenfeld, Wilson   +68 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Mark My Words! Linguistic Style Accommodation in Social Media

, 2011
The psycholinguistic theory of communication accommodation accounts for the general observation that participants in conversations tend to converge to one another's communicative behavior: they coordinate in a variety of dimensions including choice of ...
Danescu-Niculescu-Mizil, Cristian, Dumais, Susan, Gamon, Michael   +2 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

“Can I Use My Leg Too?” Dancing with Uncertainty: Exploring Probabilistic Thinking Through Embodied Learning in a Jerusalem Art High School Classroom

Education Sciences
Despite increased interest in embodied learning, the role of sensorimotor activity in shaping students’ probabilistic reasoning remains underexplored. This design-based study examines how high school students develop key probabilistic concepts, including
Dafna Efron, Alik Palatnik
doaj   +1 more source

Theoretical Contributions to Three Generalized Versions of the Celebioglu–Cuadras Copula

Analytics, 2023
Copulas are probabilistic functions that are being used more and more frequently to describe, examine, and model the interdependence of continuous random variables.
Christophe Chesneau
doaj   +1 more source