Results 71 to 80 of about 40,428 (287)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Characterizing Distribution Rules for Cost Sharing Games [PDF]
, 2013 In noncooperative cost sharing games, individually strategic agents choose resources based on how the welfare (cost or revenue) generated at each resource (which depends on the set of agents that choose the resource) is distributed.
Gopalakrishnan, Ragavendran +1 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Annales de Didactique et de Sciences Cognitives, 2020 The purpose of this contribution is to characterize the work of a teacher on simulations in probability in grade 9 course in France (14-15 year-old students).
Blandine Masselin
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
A probabilistic position value [PDF]
In this article, we generalize the position value, defined by Meessen (1988) for the class of deterministic communication situations, to the class of generalized probabilistic communication situations (G´omez et al. (2008)).
Conrado Manuel +2 more
core
Probabilistic Logic Programming and Bayesian Networks [PDF]
, 1995 We present a probabilistic logic programming framework that allows the representation of conditional probabilities. While conditional probabilities are the most commonly used method for representing uncertainty in probabilistic expert systems, they have ...
Liem Ngo, Peter Haddawy
core +1 more source
Information-theoretic analysis of commercial microwave link and environmental variables in rainfall estimation [PDF]
Atmospheric Measurement TechniquesCommercial microwave links (CMLs) are opportunistic rainfall sensors that provide indirect rainfall estimates from attenuation data. This is achieved by separating raindrop path attenuation from observed total loss and converting it to rainfall intensity
A. Špačková, M. Fencl, V. Bareš
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source