Results 61 to 70 of about 40,428 (287)
An analysis of the exponential decay principle in probabilistic trust models [PDF]
Research in models for experience-based trust management has either ignored the problem of modelling and reasoning about dynamically changing principal behaviour, or provided ad hoc solutions to it. Probability theory provides a foundation for addressing
Krukow, Karl Tikjøb +5 more
core +1 more source
Weighted scoringRules: Emphasizing Particular Outcomes When Evaluating Probabilistic Forecasts
When predicting future events, it is common to issue forecasts that are probabilistic, in the form of probability distributions over the range of possible outcomes. Such forecasts can be evaluated using proper scoring rules.
Sam Allen
doaj +1 more source
We study the existence of solutions to the problem \[ \begin{cases} \Delta u+K(x) f(u)=0 \quad & \text{ in } D \\ u>0 & \text{ in } D \\ u=0 & \text{ on } \partial D. \end{cases} \tag{I} \] Our goal is to prove an existence theorem for problem (I) in a general setting by using Brownian path integration method and the potential theory.
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
On-Orbit Manoeuvring Using Superquadric Potential Fields [PDF]
On-orbit manoeuvring represents an essential process in many space missions such as orbital assembly, servicing and reconfiguration. A new methodology, based on the potential field method along with superquadric repulsive potentials, is discussed in this
Badawy, Ahmed
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Opinion dynamics with confirmation bias. [PDF]
Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one's preexisting beliefs. It is omnipresent in psychology, economics, and even scientific practices.
Armen E Allahverdyan, Aram Galstyan
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Despite increased interest in embodied learning, the role of sensorimotor activity in shaping students’ probabilistic reasoning remains underexplored. This design-based study examines how high school students develop key probabilistic concepts, including
Dafna Efron, Alik Palatnik
doaj +1 more source

