Results 61 to 70 of about 7,822,373 (334)

Algorithmic probability

open access: yesScholarpedia, 2007
Algorithmic "Solomonoff" Probability (AP) assigns to objects an a priori probability that is in some sense universal. This prior distribution has theoretical applications in a number of areas, including inductive inference theory and the time complexity analysis of algorithms.
Hutter, M., Legg, S., Vitanyi, P.M.B.
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A Statistical Variance Components Framework for Mapping Imprinted Quantitative Trait Locus in Experimental Crosses

open access: yesJournal of Probability and Statistics, 2009
Current methods for mapping imprinted quantitative trait locus (iQTL) with inbred line crosses assume fixed QTL effects. When an iQTL segregates in experimental line crosses, combining different line crosses with similar genetic background can improve ...
Gengxin Li, Yuehua Cui
doaj   +1 more source

Quantifying the Density of mmWave NR Deployments for Provisioning Multi-Layer VR Services

open access: yesFuture Internet, 2021
The 5G New Radio (NR) technology operating in millimeter wave (mmWave) frequency band is designed for support bandwidth-greedy applications requiring extraordinary rates at the access interface. However, the use of directional antenna radiation patterns,
Vitalii Beschastnyi   +6 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

STANCE: a unified statistical model to detect cell-type-specific spatially variable genes in spatial transcriptomics

open access: yesNature Communications
One of the major challenges in spatial transcriptomics is to detect spatially variable genes (SVGs), whose expression patterns are non-random across tissue locations.
Haohao Su   +3 more
doaj   +1 more source

Dynamic SNR, Spectral Efficiency, and Rate Characterization in 5G/6G mmWave/sub-THz Systems with Macro- and Micro-Mobilities

open access: yesFuture Internet
The performance of 5G/6G cellular systems operating in millimeter wave (mmWave, 30–100 GHz) and sub-terahertz (sub-THz, 100–300 GHz) bands is conventionally assessed by utilizing the static distributions of user locations.
Darya Ostrikova   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

High Dimensional Probability

open access: yes, 2006
About forty years ago it was realized by several researchers that the essential features of certain objects of Probability theory, notably Gaussian processes and limit theorems, may be better understood if they are considered in settings that do not ...
Giné, Evarist   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy