Results 71 to 80 of about 7,822,373 (334)
As examples such as the Monty Hall puzzle show, applying conditioning to update a probability distribution on a ``naive space'', which does not take into account the protocol used, can often lead to counterintuitive results. Here we examine why. A criterion known as CAR (``coarsening at random'') in the statistical literature characterizes when ...
Grunwald, P. D., Halpern, J. Y.
openaire +5 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Conditional probability estimation [PDF]
This paper studies in particular an aspect of the estimation of conditional probability distributions by maximum likelihood that seems to have been overlooked in the literature on Bayesian networks: The information conveyed by the conditioning event ...
Cattaneo, Marco
core
Compressing Probability Distributions
We show how to store good approximations of probability distributions in small ...
Adler +9 more
core +3 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The paper opens with a brief historical sketch of the many varied conceptions of the subject which have been considered. Confined to the propositional level, a logic is then presented in which the notion of probability replaces that of truth. Superficially a many-valued logic, it differs from what has heretofore been studied as many-valued logic in ...
openaire +2 more sources
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The exchange rate is an important variable in international trade which is used as a parameter to determine a country’s international competitiveness and indicates the position of the country’s economy. A change in the exchange rate of the Kenya shilling
Charline Uwilingiyimana +3 more
doaj +1 more source

