Results 51 to 60 of about 8,108,772 (295)
Buildings, 2023 According to the current standards for prefabricated buildings, the dimensional tolerances of components are usually determined by experience, lacking a theoretical basis. This work demonstrates the mathematical distribution of the dimensional deviations
Hao Long +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Geosciences, 2020 Probabilistic models for sub-daily rainfall predictions are important tools for understanding catchment hydrology and estimating essential rainfall inputs for agricultural and ecological studies.
Md Masud Hasan +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Estimate the probability density function of maximum temperature for the Middle East
Przegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2020 Pollution is one reasons for increase temperature which leads to increase the heat waves which have large socioeconomic and healthy impacts on Middle East.
Iqbal K. Al-Ataby, Amani I. Al-Tmimi
doaj +1 more source
A best-fit probability distribution for the estimation of rainfall in northern regions of Pakistan
, 2016 This study was designed to find the best-fit probability distribution of annual maximum rainfall based on a twenty-four-hour sample in the northern regions of Pakistan using four probability distributions: normal, log-normal, log-Pearson type-III and ...
M. Amin, M. Rizwan, A. A. Alazba
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
REMARKS ON THE FORMULA FOR THE MOMENTS OF THE PÓLYA PROBABILITY DISTRIBUTION
Acta Universitatis Lodziensis. Folia Oeconomica, 2015 The probability distribution of a random variable can be characterized by some numbers called parameters of the distribution. The moments belong to the most frequently used parameters.
Tadeusz Gerstenkorn
doaj
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source