Results 61 to 70 of about 7,036,065 (293)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Age-of-Information Distribution in Slotted ALOHA
IEEE AccessAge-of-Information (AoI) is a new performance metric for critical networked cyber-physical systems (CPS), where performance depends on how quickly fresh data is received in update packets.
Dieter Fiems, Alexey Vinel
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Applications of Fuss-Catalan Numbers to Success Runs of Bernoulli Trials
Journal of Probability and Statistics, 2016 In a recent paper, the authors derived the exact solution for the probability mass function of the geometric distribution of order k, expressing the roots of the associated auxiliary equation in terms of generating functions for Fuss-Catalan numbers ...
S. J. Dilworth, S. R. Mane
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
A probablistic proof of the series representation of the MacDonald function with applications
International Journal of Mathematics and Mathematical Sciences, 1998 A series representation of the Macdonald function is obtained using the properties of a probability density function and its moment generating function. Some applications of the result are discussed and an open problem is posed.
M. Aslam Chaudhry, Munir Ahmad
doaj +1 more source
Joint probability generating function for a vector of arbitrary indicator variables [PDF]
, 2005 We obtain formulas for the probability generating function of general multivariate Bernoulli distributions, and for the moment generating function of the aggregate claim amount for individual risk models with dependencies.
Ekaterina T. Kolkovska +5 more
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Weighted Sum of Correlated Lognormals: Convolution Integral Solution [PDF]
, 2011 Probability density function (pdf) for sum of n correlated lognormal variables is deducted as a special convolution integral. Pdf for weighted sums (where weights can be any real numbers) is also presented.
Nagy, Tamás
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source