Results 71 to 80 of about 1,021,568 (282)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Full counting statistics of information content
, 2018 We review connections between the cumulant generating function of full counting statistics of particle number and the R\'enyi entanglement entropy. We calculate these quantities based on the fermionic and bosonic path-integral defined on multiple Keldysh
A. Petrescu +44 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Generalized Systems Governing Probability Density Functions [PDF]
, 2016 So far we have considered one-dimensional and two-dimensional release processes. When the channel can take on two states—open or closed—we have seen that the associated probability density functions are governed by 2 × 2 systems of partial differential equations.
Aslak Tveito, Glenn T. Lines
openaire +1 more source
Continuously-variable survival exponent for random walks with movable partial reflectors
, 2001 We study a one-dimensional lattice random walk with an absorbing boundary at the origin and a movable partial reflector. On encountering the reflector, at site x, the walker is reflected (with probability r) to x-1 and the reflector is simultaneously ...
C. Kaiser +24 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
An alternative hyper-Poisson distribution
Statistica, 2013 An alternative form of hyper-Poisson distribution is introduced through its probability mass function and studies some of its important aspects such as mean, variance, expressions for its raw moments, factorial moments, probability generating function ...
C. Satheesh Kumar, B. Unnikrishnan Nair
doaj +1 more source
Sharp bounds by probability-generating functions and variable drift [PDF]
Proceedings of the 13th annual conference on Genetic and evolutionary computation, 2011 We introduce to the runtime analysis of evolutionary algorithms two powerful techniques: probability-generating functions and variable drift analysis. They are shown to provide a clean framework for proving sharp upper and lower bounds. As an application, we improve the results by Doerr et al. (GECCO~2010) in several respects. First, the upper bound on
Doerr, B., Fouz, M., Witt, C.
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Appell polynomials and their relatives II. Boolean theory
, 2007 The Appell-type polynomial family corresponding to the simplest non-commutative derivative operator turns out to be connected with the Boolean probability theory, the simplest of the three universal non-commutative probability theories (the other two ...
Anshelevich, Michael
core +2 more sources
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source