Results 61 to 70 of about 2,906,323 (237)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Some Limiting Laws in Non-Commutative Probability

Axioms
In this article, we provide some new limiting laws related to the free multiplicative law of large numbers and involving free and Boolean additive convolutions.
Ayed. R. A. Alanzi, Raouf Fakhfakh, Fatimah Alshahrani   +2 more
doaj   +1 more source

Regular extension operators for partial fuzzy (pseudo)metrics [PDF]

Математичні Студії, 2011
Using the fuzzy modification of the Prokhorov metric on the set of probability measures we prove the theorem on existence of simultaneous extensions of partial fuzzy metrics (for the Lukasiewicz t-norm) defined on closed subsets of a compact metrizable ...
A. Savchenko
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

On the Čech-Completeness of the Space of τ-Smooth Idempotent Probability Measures

Axioms
For the set I(X) of probability measures on a compact Hausdorff space X, we propose a new way to introduce the topology by using the open subsets of the space X.
Ljubiša D. R. Kočinac, Adilbek A. Zaitov, Muzaffar R. Eshimbetov   +2 more
doaj   +1 more source

Bernoulli trials and permutation statistics

International Journal of Mathematics and Mathematical Sciences, 1992
Several coin-tossing games are surveyed which, in a natural way, give rise to “statistically” induced probability measures on the set of permutations of {1,2,…,n} and on sets of multipermutations.
Don Rawlings
doaj   +1 more source

A discrete limit theorem for the periodic Hurwitz zeta-function. II

Lietuvos Matematikos Rinkinys, 2016
In the paper, we prove a limit theorem of discrete type on the weak convergence of probability measures on the complex plane for the periodic Hurwitz zeta-function.
Audronė Rimkevičienė
doaj   +1 more source