Results 71 to 80 of about 4,158,523 (273)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Some New Inequalities for Jeffreys Divergence Measure in Information Theory [PDF]

open access: yes, 2000
Some new inequalities for the well-known Jeffreys divergence measure in Information Theory are ...
Sunde, J   +2 more
core   +4 more sources

Some Limiting Laws in Non-Commutative Probability

open access: yesAxioms
In this article, we provide some new limiting laws related to the free multiplicative law of large numbers and involving free and Boolean additive convolutions.
Ayed. R. A. Alanzi   +2 more
doaj   +1 more source

Regular extension operators for partial fuzzy (pseudo)metrics [PDF]

open access: yesМатематичні Студії, 2011
Using the fuzzy modification of the Prokhorov metric on the set of probability measures we prove the theorem on existence of simultaneous extensions of partial fuzzy metrics (for the Lukasiewicz t-norm) defined on closed subsets of a compact metrizable ...
A. Savchenko
doaj  

On uniform local dispersion on a family of G-orbits [PDF]

open access: yes, 1986
Trockel W. On uniform local dispersion on a family of G-orbits. Journal of Mathematical Analysis and Applications. 1986;118(1):173-179.Consider a topological space T which is the union of a family of G-orbits, where G is a locally euclidean group G ...
Trockel, Walter   +1 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

On the Wasserstein Median of Probability Measures

open access: yesJournal of Computational and Graphical Statistics
The primary choice to summarize a finite collection of random objects is by using measures of central tendency, such as mean and median. In the field of optimal transport, the Wasserstein barycenter corresponds to the Fréchet or geometric mean of a set of probability measures, which is defined as a minimizer of the sum of squared distances to each ...
Kisung You   +2 more
openaire   +5 more sources

INTRODUCTION TO NEUTROSOPHIC STATISTICS [PDF]

open access: yes, 2014
Although the neutrosophic statistics has been defined since 1996, and published in the 1998 book Neutrosophy. / Neutrosophic Probability, Set, and Logic, it has not been developed since now.
Smarandache, Florentin
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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