Results 81 to 90 of about 2,906,323 (237)
Nonhomogeneous distributions and optimal quantizers for Sierpi\'nski carpets
, 2016 The purpose of quantization of a probability distribution is to estimate the probability by a discrete probability with finite support. In this paper, a nonhomogeneous probability measure $P$ on $\mathbb R^2$ which has support the Sierpi\'nski carpet ...
Roychowdhury, Mrinal Kanti
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Probability measure monad on the category of ultrametric spaces
Applied General Topology, 2008 The set of all probability measures with compact support on an ultrametric space can be endowed with a natural ultrametric. We show that the functor of probability measures with finite supports (respectively compact supports) forms a monad in the ...
O.B. Hubal, M.M. Zarichnyi
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Conditional Optimal Sets and the Quantization Coefficients for Some Uniform Distributions
MathematicsBucklew and Wise (1982) showed that the quantization dimension of an absolutely continuous probability measure on a given Euclidean space is constant and equals the Euclidean dimension of the space, and the quantization coefficient exists as a finite ...
Evans Nyanney +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Axioms, 2012 We present a simple and clear foundation for finite inference that unites and significantly extends the approaches of Kolmogorov and Cox. Our approach is based on quantifying lattices of logical statements in a way that satisfies general lattice ...
Kevin H. Knuth, John Skilling
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
"Uniform Measures On Inverse Limit Spaces" [PDF]
Motivated by problems from dynamic economic models, we consider the problem of defining a uniform measure on inverse limit spaces. Let f be a function from a compact metric space X into itself where f is continuous, onto and piecewise one-to-one.
David R. Stockman
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