Results 31 to 40 of about 1,787,476 (292)

Failure Probability Estimation Using Asymptotic Sampling and Its Dependence upon the Selected Sampling Scheme

open access: yesTransactions of the VŠB: Technical University of Ostrava, Civil Engineering Series, 2017
The article examines the use of Asymptotic Sampling (AS) for the estimation of failure probability. The AS algorithm requires samples of multidimensional Gaussian random vectors, which may be obtained by many alternative means that influence the ...
Martinásková Magdalena   +1 more
doaj   +1 more source

Maximally Consistent Sampling and the Jaccard Index of Probability Distributions

open access: yes, 2018
We introduce simple, efficient algorithms for computing a MinHash of a probability distribution, suitable for both sparse and dense data, with equivalent running times to the state of the art for both cases.
Jiang, Yunjiang, Moulton, Ryan
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

On the inclusion probabilities in some unequal probability sampling plans without replacement

open access: yes, 2012
Comparison results are obtained for the inclusion probabilities in some unequal probability sampling plans without replacement. For either successive sampling or H\'{a}jek's rejective sampling, the larger the sample size, the more uniform the inclusion ...
Yu, Yaming
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Fast simulation of the leaky bucket algorithm [PDF]

open access: yes, 1994
We use fast simulation methods, based on importance sampling, to efficiently estimate cell loss probability in queueing models of the Leaky Bucket algorithm.
Hagesteijn, Gertjan A.   +2 more
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

CONVENIENCE SAMPLING: A REVIEW AND GUIDELINES FOR QUANTITATIVE RESEARCH [PDF]

open access: yesJournal of Applied Structural Equation Modeling
Convenience sampling is widely used in business and management research, yet its application in quantitative studies is often criticized for lacking rigor and transparency.
Mumtaz Ali Memon   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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