Results 51 to 60 of about 3,700,207 (308)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Sweet tweets! Evaluating a new approach for probability-based sampling of Twitter

EPJ Data Science, 2022
As survey costs continue to rise and response rates decline, researchers are seeking more cost-effective ways to collect, analyze and process social and public opinion data.
Trent D. Buskirk, Brian P. Blakely, Adam Eck, Richard McGrath, Ravinder Singh, Youzhi Yu   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Mobile Cloud Data Storage Based on Gibbs Sampling and Probability Distribution Estimation [PDF]

Jisuanji gongcheng, 2017
In order to improve the computing and storage capacity of mobile cloud data storage remote server,this paper proposes an improved mobile cloud data storage algorithm.Firstly,it constructs resampling expected propagation time calculation model by ...
LI Youling,CHANG Zhiquan
doaj   +1 more source

Robust Models in Probability Sampling

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1998
Summary In the estimation of a population mean or total from a random sample, certain methods based on linear models are known to be automatically design consistent, regardless of how well the underlying model describes the population. A sufficient condition is identified for this type of robustness to model failure; the condition, which
Firth, D., Bennett, K. E.
openaire   +2 more sources

Evaluation of the role of location and distance in recruitment in respondent-driven sampling [PDF]

, 2011
Household location affected the overall probability of recruitment, and the probability of recruitment by a specific recruiter. Patterns of recruitment do not appear to have greatly biased estimates in this study.
Copas, Andrew, White Richard G, Hayes, Richard J., Sonnenberg Pam, Seeley, J, McCreesh Nicky, Janet Seeley, Lisa G Johnston, Sonnenberg, Pam, Hayes Richard J, Frost Simon DW, Johnston, Lisa G., Hayes, Richard J, White, Richard G, White, Richard G., Sonnenberg, P, Frost, Simon DW, Copas Andrew, Copas, A, Johnston, LG, Richard G White, Seeley, Janet, Andrew Copas, McCreesh, Nicky, Nicky McCreesh, Simon DW Frost, Johnston Lisa G, Frost, SD, Pam Sonnenberg, Richard J Hayes, Frost, Simon D. W., McCreesh, N, White, RG, Johnston, Lisa G, Seeley Janet, Hayes, RJ   +35 more
core   +4 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Estimating Income Variances by Probability Sampling: A Case Study [PDF]

Pakistan Journal of Commerce and Social Sciences, 2010
The main focus of the study is to estimate variability in income distribution of households by conducting a survey. The variances in income distribution have been calculated by probability sampling techniques.
Akbar Ali Shah, M. Aleem
doaj