Results 61 to 70 of about 481,004 (314)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

An Accurate Sample Rejection Estimator of the Outage Probability With Equal Gain Combining [PDF]

, 2020
Nadhir Ben Rached, Abla Kammoun, Mohamed‐Slim Alouini, Raúl Tempone   +3 more
openalex   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Optimising species detection probability and sampling effort in lake fish eDNA surveys [PDF]

Metabarcoding and Metagenomics
Environmental DNA (eDNA) metabarcoding is transforming biodiversity monitoring in aquatic environments. Such an approach has been developed and deployed for monitoring lake fish communities in Great Britain, where the method has repeatedly shown a ...
Graham S. Sellers, Christopher L. Jerde, Lynsey R. Harper, Marco Benucci, Cristina Di Muri, Jianlong Li, Graeme Peirson, Kerry Walsh, Tristan Hatton-Ellis, Willie Duncan, Alistair Duguid, Dave Ottewell, Nigel Willby, Alan Law, Colin W. Bean, Ian J. Winfield, Daniel S. Read, Lori Lawson Handley, Bernd Hänfling   +18 more
doaj   +3 more sources

New estimators for estimating population total: an application to water demand in Thailand under unequal probability sampling without replacement for missing data. [PDF]

PeerJ, 2022
Ponkaew C, Lawson N.
europepmc   +1 more source

Estimating the probability that a given vector is in the convex hull of a random sample [PDF]

, 2023
Satoshi Hayakawa, Terry Lyons, Harald Oberhauser   +2 more
openalex   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Line Sampling with Probability Proportional to The Geometrical Average Area Per Tree in The Stand [PDF]

Floresta e Ambiente
The study proposes a sampling method, termed the probability proportional to the average geometric area of occupation, method in which a set of trees along a row is selected as the sampling unit with a probability proportional to the geometrical average ...
Sylvio Péllico Netto, Alexandre Behling, Ataides Marinheski Filho, Ângelo Augusto Ebling, Claiton Nardini   +4 more
doaj   +1 more source