Results 101 to 110 of about 346,818 (384)

Strain-Specificity and Disease-Specificity of Probiotic Efficacy: A Systematic Review and Meta-Analysis

Frontiers in Medicine, 2018
Background As the use and diversity of probiotic products expands, the choice of an appropriate type of probiotic is challenging for both medical care professionals and the public alike.
L. Mcfarland, C. Evans, E. Goldstein
semanticscholar   +1 more source

Safety of probiotics [PDF]

Clinical and Translational Allergy, 2011
Probiotics are used by millions of people for their documented or anticipated health benefits. They usu-ally belong to the genera lactobacilli and bifidobacteria and are part of the normal flora. They have been studied in a wide variety of diseases and in the prevention of inflammatory and infectious dis-eases.
openaire   +3 more sources

Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li, Linxin Dai, Meisi Lin, Shuang He, Hongye Du, Dasheng Lin, Yanbin Wang, Fenglian Zhang, Sian Tao, Xiaoluo Sun, Xinggui Huang, Haihui Liu, Qian Wang, Lingling He, Kunhe Wu, Jieshu You, Minyue Zhang, Chaomei Fu, He Tu, Naijing Ye, Jibin Liu, Fei Gao   +21 more
wiley   +1 more source

Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients

Nature Network Boston, 2019
Probiotics are routinely administered to hospitalized patients for many potential indications1 but have been associated with adverse effects that may outweigh their potential benefits2–7.
I. Yelin, Kelly B. Flett, Christina Merakou, Preeti Mehrotra, J. Stam, E. Snesrud, M. Hinkle, E. Lesho, P. McGann, A. McAdam, Thomas J. Sandora, R. Kishony, G. Priebe   +12 more
semanticscholar   +1 more source

β‐Glucuronidase‐Expressing Lactobacillus reuteri Triggers Irinotecan Enterotoxicity Through Depleting the Regenerative Epithelial Stem/Progenitor Pool

Advanced Science, EarlyView.
XLP mitigated CPT11 mucositis by suppressing GUS‐expressing microbes, notably L. reuteri, and diminishing bacterial GUS activity, consequently reducing SN38 accumulation to protect the intestinal epithelium. This preservation of the mucosal stem cell niche enabled rapid regeneration of secretory lineages such as mucin‐producing goblet cells, which ...
Bei Yue, Ruiyang Gao, Ling Zhao, Donghui Liu, Cheng Lv, Ziyi Wang, Fangbin Ai, Beibei Zhang, Zhilun Yu, Xiaolong Geng, Hao Wang, Kang Wang, Kaixian Chen, Chenghai Liu, Zhengtao Wang, Wei Dou   +15 more
wiley   +1 more source

Eriobotrya japonica Fermentation with Plant-Derived Lactiplantibacillus plantarum MSC-5T Ameliorates Antioxidant Activity in HEK293 Cells

Fermentation
Oxidative stress from an excess of radical compounds generally impacts apoptosis and inflammation. The use of probiotics, therefore, has emerged as a favorable tool to suppress the formation of reactive oxygen species.
Narandalai Danshiitsoodol, Yusuke Inoue, Sachiko Sugimoto, Shrijana Shakya, Masafumi Noda, Masanori Sugiyama   +5 more
doaj   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Proteomics as a quality control tool of pharmaceutical probiotic bacterial lysate products [PDF]

, 2013
Probiotic bacteria have a wide range of applications in veterinary and human therapeutics. Inactivated probiotics are complex samples and quality control (QC) should measure as many molecular features as possible.
A Albalat, A Thomsen, AC Ouwehand, AV Simionato, Benoit Foligne, BGVV Arbeitsgruppe, C Santini, D Theodorescu, DM Carty, DM Good, E Dehlink, E Schiffer, F Gaggia, F Indrio, Günter Klein, H Mischak, H Mischak, Harald Mischak, J Hoffmann, J Jantos-Siwy, J Jähne, J Siwy, Janosch Hoffmann, JM Hamilton-Miller, Joost P. Schanstra, Justyna Siwy, K Savijoki, Kurt Zimmermann, L Sanchez-Hernandez, L Zhang, M Cazzola, MC Collado, ME Sanders, N Neuhoff, P Enck, P Hommerson, P Zürbig, P Zürbig, PM Sherman, R Haselberg, RGK Leuschner, S Lau, S Wittke, T Giese, T Volz, T Volz, Y Ohashi, Y Sun   +47 more
core   +3 more sources

Human-origin probiotic cocktail increases short-chain fatty acid production via modulation of mice and human gut microbiome

Scientific Reports, 2018
The gut bacteria producing metabolites like short-chain fatty acids (SCFAs; e.g., acetate, propionate and butyrate), are frequently reduced in Patients with diabetes, obesity, autoimmune disorders, and cancers.
R. Nagpal, Shaohua Wang, Shokouh Ahmadi, Joshua Hayes, Jason Gagliano, S. Subashchandrabose, D. Kitzman, Thomas Becton, Russel Read, H. Yadav   +9 more
semanticscholar   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

Advanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma, Shenao Fu, Jun Tan, Ying Han, Yihong Chen, Xiangying Deng, Hong Shen, Shan Zeng, Yinghui Peng, Changjing Cai   +9 more
wiley   +1 more source