Results 31 to 40 of about 608,139 (356)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Kemampuan Literasi Matematis Siswa Ditinjau dari Kemampuan Pemecahan Masalah Siswa SMP di Pontianak [PDF]

open access: yes, 2016
This research aims to describe student's mathmatical literacy ability in terms of problem solving skill in Junior High School Pontianak. This research used descriptive method with case study research design.
Hartoyo, A. (Agung)   +2 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Terapi Kognitif Perilaku untuk Mengurangi Masalah Perilaku pada Anak Conduct Disorder

open access: yesJIP (Jurnal Intervensi Psikologi), 2017
This research goals is to know whether problem solving skill training (PSST) can be effective to decrease conduct problem to a child with conduct disorder.
Dinda Septiani, Eka Ervika
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Kemampuan Pemecahan Masalah Siswa dengan Penerapan Modeling Instruction pada Konsep Listrik Dinamis [PDF]

open access: yes, 2015
This research aims to describe the problem solving skill of student in class X-7 SMA Negeri 5 Pekanbaru with the implementation of Modeling Instruction in lesson dynamic electric.
Azhar, A. (Azhar)   +2 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

THE PROFILE OF STUDENTS’ PROBLEM-SOLVING SKILLS TOWARD ENVIRONMENTAL POLLUTION TOPIC

open access: yesAssimilation, 2023
Problem-solving is an essential skill that must be possessed by students, especially in learning biology. The purpose of this research is to determine the profile of students’ problem-solving skills in Senior High School 10 Palembang on environmental ...
Kurnia Utami   +2 more
doaj   +1 more source

The overview of problem solving skill through online social networking platform [PDF]

open access: yes, 2015
Problem-solving skill is one of the 21st century skills needed by students to be competitive in the future working world. However, international assessment results have shown Malaysian students are still weak in problem solving and many graduates face ...
Abdullah, Zaleha   +4 more
core  

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