Results 51 to 60 of about 6,347,393 (285)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Analysis of the Comparison of Science Literacy Skills of Students at MTS Nurul Huda Situbondo in Solving PISA Science Problems

Edukasia, 2023
PISA (Program for International Student Assessment) is an international assessment designed to measure students' literacy abilities in various disciplines, including science.
Alivinda Aulia Safira Musyarofah, Azza Liarista Anggraini, Sudarti, Rif’ati Dina Handayani, Muhammad Jamhari, Haeruddin   +5 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Kemampuan Pemecahan Masalah Matematis Siswa dalam Menyelesaikan Soal PISA pada Topik Geometri

Jurnal Elemen, 2020
This study aims to describe the mathematical problem-solving ability of students in solving geometry problem of Programme for International Student Assessment (PISA).
Anas Ma'ruf Annizar, Mohammad Archi Maulyda, Gusti Firda Khairunnisa, Lailin Hijriani   +3 more
doaj  

The Correlation of Critical Thinking Skill and Science Problem-Solving Ability of Junior High School Students

Jurnal Pendidikan Sains, 2017
: This paper intends to seek the correlation of critical thinking skill and problem-solving ability of students on Natural Sciences Subject within Junior High School in Ecosystem topic.
Irma Lismayani, Parno Parno, Susriyati Mahanal   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Toys as Instructional Tools in Developing Problem-Solving Skills in Children [PDF]

, 2010
This study determined possible uses of toys as instructional tools in the development of problem-solving skills among preschoolers. It aimed to identify the common toys found in preschool and how these toys can be used in lessons to develop students ...
Clavio, Josefa Carina V., Fajardo, Amelia C.   +1 more
core  

International Center for Studies in Creativity: curricular overview and impact of instruction on the creative problem- solving attitudes of graduate students

, 2016
International center for studies in creativity: curricular overview and impact of instruction on the creative problem solving attitudes of graduate students. In C.
Acar, Selçuk, Puccio, Gerard J., Mathers, Susan Keller, Çayırdağ, Nur   +3 more
core   +1 more source

The description of students’ mathematical problem-solving skill and self-regulation

International Journal of Science and Applied Science: Conference Series, 2017
The research aimed to describe the students’ mathematics problem-solving skill and self-regulation in SMP Negeri 8 Purwokerto used Miles and Huberman’s model of cover reduction, serve, and conclusion.
Ani Nurwijayanti, Akhmad Jazuli, Erni Widyastuti   +2 more
doaj   +1 more source