Results 41 to 50 of about 6,347,393 (285)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Adaptive expert decision making: Skilled chess players search more and deeper [PDF]
, 2004 Previous research has suggested that depth of search in chess does not increase much as a function of skill. We submitted players to a problem-solving task with complex positions.
Campitelli, G, Gobet, F
core +5 more sources
Indonesian Contemporary Nursing Journal, 2018 Background: High demands in all conditions require proffesional health workers. In dealing with patients, health workers need high emotional intelligence and problem solving skills that are qualified to deal with various problems.
Hasnah Hasnah +2 more
doaj +1 more source
THE PROFILE OF STUDENTS’ PROBLEM-SOLVING SKILLS TOWARD ENVIRONMENTAL POLLUTION TOPIC
Assimilation, 2023 Problem-solving is an essential skill that must be possessed by students, especially in learning biology. The purpose of this research is to determine the profile of students’ problem-solving skills in Senior High School 10 Palembang on environmental ...
Kurnia Utami +2 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
THE ABILITY TO SOLVE PROBLEMS WITH INFORMATIC RESOURCES IN THE FORMATION OF THE PRIMARY TEACHER [PDF]
Varela, 2018 The treatment of problem solving through computer resources has a transcendental importance for the life of young people in society. Cuban education promotes the resolution of computer problems from an early age, through the school curriculum.
Keila Irene Díaz Tejera +1 more
doaj
Students Ability to Solve Mathematical Problem Through Online Learning During Covid-19 Pandemic
Al Khawarizmi, 2022 The purpose of this study is to examine the solving skill of students on mathematical problem through online learning during COVID-19 pandemic, particularly in solving the problem related area and perimeter of trapezium.
Budi Azhari +3 more
doaj +1 more source