Results 31 to 40 of about 3,247,454 (344)

What Makes A Court Problem-Solving: Universal Performance Indicators for Problem-Solving Justice [PDF]

open access: yes, 2010
This report identifies a set of universal performance indicators for specialized "problem-solving courts" and related experiments in problem-solving justice.
Adam Mansky   +2 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

KOMPARASI KEMAMPUAN PEMECAHAN MASALAH ANTARA PEMBELAJARAN CREATIVE PROBLEM SOLVING DAN PROBLEM POSING

open access: yesUnnes Journal of Mathematics Education, 2015
Tujuan penelitian ini untuk mengetahui apakah kelas yang dikenai pembelajaran Creative Problem Solving (CPS) dan Problem Posing (PP) dapat mencapai ketuntasan klasikal dan untuk mengetahui manakah kemampuan pemecahan masalah yang lebih baik antara siswa ...
Moh. Firman Amardani Saputra   +1 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Pengaruh Model Pembelajaran Creative Problem Solving Terhadap Keterampilan Pemecahan Masalah dan Hasil Belajar Kognitif Siswa

open access: yesPrisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2017
This research with the aim to know the influence of the use of Creative Problem solving learning model on problem solving skills and cognitive learning outcomes of grade X SMA Islam Al-Ma'arif Pandan Indah Lesson 2016/2017. Population in this research is
Rosmianti Lestari Mbembok   +2 more
doaj   +1 more source

Pengaruh Problem Solving Berbantuan Booklet B2m terhadap Respon dan Hasil Belajar Siswa Sman 9 Pontianak [PDF]

open access: yes, 2016
Tujuan dari penelitian ini adalah untuk menentukan pengaruh problem solving berbantuan booklet B2M terhadap respon dan hasil belajar siswa SMA Negeri 9 Pontianak pada materi larutan penyangga.
Enawaty, E. (Eny)   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Prediction and Classification of Phenol Contents in Cnidium officinale Makino Using a Stacking Ensemble Model in Climate Change Scenarios

open access: yesAgronomy
Recent studies have focused on using big-data-based machine learning to address the effects of climate change scenarios on the production and quality of medicinal plants.
Hyunjo Lee   +5 more
doaj   +1 more source

PENGARUH MODEL PEMBELAJARAN CREATIVE PROBLEM SOLVING BERBANTUAN MEDIA MAPLE 11 TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS

open access: yesAl-Jabar, 2015
Lack of mathematical problem solving ability of students in Bandar Lampung MAN 2 due learners trouble completing math problems and students rarely ask questions or express ideas workmanship. This study aims to determine the effect of mathematical problem
Muhamad Syazali
doaj   +1 more source

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