Results 31 to 40 of about 6,464,492 (299)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Toys as Instructional Tools in Developing Problem-Solving Skills in Children [PDF]
This study determined possible uses of toys as instructional tools in the development of problem-solving skills among preschoolers. It aimed to identify the common toys found in preschool and how these toys can be used in lessons to develop students ...
Clavio, Josefa Carina V. +1 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Tujuan penelitian ini untuk mengetahui apakah kelas yang dikenai pembelajaran Creative Problem Solving (CPS) dan Problem Posing (PP) dapat mencapai ketuntasan klasikal dan untuk mengetahui manakah kemampuan pemecahan masalah yang lebih baik antara siswa ...
Moh. Firman Amardani Saputra +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Coaching by Problem Solving (Convergent Discovery)
When Coaching by Problem Solving, the coach’s role is to make the decision about the concept to be discovered. The coach designs a problem or question that requires the players to come up with the questions and their own sequence to converge on an answer.
Pill, Shane +7 more
core +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Recent studies have focused on using big-data-based machine learning to address the effects of climate change scenarios on the production and quality of medicinal plants.
Hyunjo Lee +5 more
doaj +1 more source
Lack of mathematical problem solving ability of students in Bandar Lampung MAN 2 due learners trouble completing math problems and students rarely ask questions or express ideas workmanship. This study aims to determine the effect of mathematical problem
Muhamad Syazali
doaj +1 more source

