Results 31 to 40 of about 6,229,141 (293)

Learning problem-solving concepts by reflecting on problem solving [PDF]

open access: yes, 1994
Learning and problem solving are intimately related: problem solving determines the knowledge requirements of the reasoner which learning must fulfill, and learning enables improved problem-solving performance. Different models of problem solving, however, recognize different knowledge needs, and, as a result, set up different learning tasks.
Eleni Stroulia, Ashok K. Goel 0001
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Toys as Instructional Tools in Developing Problem-Solving Skills in Children [PDF]

open access: yes, 2010
This study determined possible uses of toys as instructional tools in the development of problem-solving skills among preschoolers. It aimed to identify the common toys found in preschool and how these toys can be used in lessons to develop students ...
Clavio, Josefa Carina V.   +1 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

KOMPARASI KEMAMPUAN PEMECAHAN MASALAH ANTARA PEMBELAJARAN CREATIVE PROBLEM SOLVING DAN PROBLEM POSING

open access: yesUnnes Journal of Mathematics Education, 2015
Tujuan penelitian ini untuk mengetahui apakah kelas yang dikenai pembelajaran Creative Problem Solving (CPS) dan Problem Posing (PP) dapat mencapai ketuntasan klasikal dan untuk mengetahui manakah kemampuan pemecahan masalah yang lebih baik antara siswa ...
Moh. Firman Amardani Saputra   +1 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Efektivitas E-Modul Sistem Pencernaan Berbasis Problem Solving Terhadap Kemampuan Pemecahan Masalah

open access: yesJIPI (Jurnal IPA dan Pembelajaran IPA), 2021
Learning during the Covid-19 pandemic has largely shifted to online learning. In response to this, it is necessary to prepare teaching materials that support online learning, one of which is the use of electronic models or e-modules.
Irvan Permana*   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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