Results 41 to 50 of about 3,247,454 (344)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Description and impact of a distance mathematics course for Grade 10 to 12 teachers
Pythagoras, 2007 This paper explores the impact of a one-year in-service distance education mathematics course that follows a problem-solving approach. The course aims to develop teachers’ mathematical thinking skills.
Gerrit Stols +2 more
doaj +1 more source
Compositionality Solves Carnap’s Problem
Erkenntnis, 2015 The standard relation of logical consequence allows for non-standard interpretations of logical constants, as was shown early on by Carnap. But then how can we learn the interpretations of logical constants, if not from the rules which govern their use?
Bonnay, Denis, Westerståhl, Dag
openaire +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Aksioma: Jurnal Program Studi Pendidikan Matematika, 2017 The problem of Addition Operation of Functions often emerges in Junior National Science and Math Olympiads at the regional level, provincial level, and national level.
Kartika Maharani Dwi Astuti +1 more
doaj +1 more source
Pengaruh Metode Problem Solving terhadap Hasil Belajar Siswa pada Konsep Koperasi dan Pengelolaan Koperasi Kelas X di Sman 11 Kota Pekanbaru [PDF]
, 2017 This research was conducted at SMAN 11 Pekanbaru with the aim to analyze problem solving method to student learning outcomes. The population in this study were students of class X IPS and Samples performed by using simple random sampling because the ...
Gimin, G. (Gimin) +2 more
core
Towards solving generic cosmological singularity problem
, 2012 The big bounce transition of the quantum FRW model in the setting of loop quantum cosmology is presented. We determine the physical self-adjoint Hamiltonian generating the dynamics. It is used to define, via the Stone theorem, an evolution operator.
Piechocki, Wlodzimierz
core +1 more source
Solving the Decompactification Problem in String Theory [PDF]
, 1996 We investigate heterotic ground states in four dimensions in which N=4 supersymmetry is spontaneously broken to N=2. N=4 supersymmetry is restored at a decompactification limit corresponding to $m_{3/2}\to 0$.
Aldazabal +46 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Creative Problem Solving [PDF]
, 2002 [Excerpt] Sometimes solutions to difficult problems are simple, if you think creatively.
Margolies, Ken
core +1 more source