Results 51 to 60 of about 3,247,454 (344)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Efektivitas Problem Solving Dalam Meningkatkan Kemampuan Memfokuskan Pertanyaan Pada Larutan Elektrolit Non-elektrolit [PDF]
, 2015 This research aimed to describe the effectiveness of problem solving in increasing question focus ability in electrolyte-nonelectrolyte solution. The population this research was 440 students from all the MIA of the 10th grade in SMA Negeri 1 Natar for ...
Rudibyani, R. B. (Ratu) +2 more
core
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Secondary School Teachers’ Perceptions about Their Problem Solving Abilities [PDF]
İnönü Üniversitesi Eğitim Fakültesi Dergisi, 2008 The purpose of the study is to determine the perceptions of high school teachers abouttheir level of problem solving skills and to find out whether their perceptions differaccording to gender, seniority, branch, marital status, how many children they ...
Hasan DEMİRTAŞ, Burhanettin DÖNMEZ
doaj
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Introductory Problem Solving in Computer Science [PDF]
, 1997 This paper describes our experiences in devising a lightweight, informal methodology for problem solving in introductory, university level, computer science.
Barnes, David J. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Investigation of the Solutions of Prizren-Kosovo Education Faculty Teachers Mathematics Problems
Prizren Social Science Journal, 2018 The aim of the study was to examination of mathematical problem-solving skills and to determine the relationship of between problem posing and problem-solving skills of teacher trainees in Prizren “Ukshin Hoti†University, Faculty of Education in ...
Münevver MUYO YILDIRIM +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source