Results 41 to 50 of about 396,482 (263)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Problematic Internet use and the diagnostic journey [PDF]

open access: yesWorld Psychiatry, 2010
Elias Aboujaoude’s thoughtful overview of problematic Internet use allows us to reflect on the various strategies currently available to buttress claims for a distinct diagnostic category along the impulsive, compulsive, and/or addiction disorders spectrum.
Nady, El-Guebaly, Tanya, Mudry
openaire   +2 more sources

Perfilando los consumidores de cannabis que autocultivan a pequeña escala

open access: yesAnales de Psicologia
El cannabis es la sustancia ilícita más consumida a nivel mundial, con una prevalencia estimada entre el 2.8 y el 5.0% de la población adulta. El auge del consumo de cannabis ha llevado a un aumento en el cultivo para el propio consumo. Como consecuencia,
Manuel Isorna   +3 more
doaj   +1 more source

The problematic use of mobile phone and mental health: A review study in Iran

open access: yesJournal of Education and Health Promotion, 2020
There is growing evidence that the problematic use of mobile phone is an evolving problem. Although some studies have noted a greater prevalence in the Middle East, intercultural differences have not been sufficiently studied to date.
Mandana Amiri   +3 more
doaj   +1 more source

Studying Social Media Burnout and Problematic Social Media use: The implication of perfectionism and metacognitions

open access: yesComputers in Human Behavior Reports, 2021
Social Media Burnout (SMB) is a relatively new Internet-related issue, and has garnered interest in research this past decade. Prior studies found significant associations between perfectionism and metacognitions with anxiety, stress-related disorders ...
Nina Harren, Vera Walburg, Henri Chabrol
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Problematic Mobile Phone and Smartphone Use Scales: A Systematic Review

open access: yesFrontiers in Psychology, 2020
The popularity of smartphones is undeniable in nearly all facets of society. Despite the many benefits attributed to the technology, concern has grown over the potential for excessive smartphone use to become problematic in nature.
Bethany Harris   +3 more
doaj   +1 more source

Problematic WhatsApp Use Among Adolescents: Linking Fear of Missing Out and Psychiatric Symptoms

open access: yesPsychiatry and Behavioral Sciences, 2021
Objective: WhatsApp (WA) is the most popular instant message application all over the world. Although communication has become easier and enjoyable with the help of this application, the overuse, and addiction of WA has become an important problem among ...
Hesna Gul   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Prevalence of problematic internet use in Slovenia [PDF]

open access: yesSlovenian Journal of Public Health, 2016
Abstract Background Internet use is an integral part of our everyday activities; however, Internet use may become problematic and harmful in a minority of cases. The majority of reported prevalence rates of problematic Internet use refer to adolescent samples, whereas epidemiological studies on ...
Macur, M   +4 more
openaire   +4 more sources

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