Results 21 to 30 of about 11,777 (251)

Exponential distribution of long heart beat intervals during atrial fibrillation and their relevance for white noise behaviour in power spectrum [PDF]

open access: yes, 2006
The statistical properties of heart beat intervals of 130 long-term surface electrocardiogram recordings during atrial fibrillation (AF) are investigated.
A. Bollmann   +34 more
core   +2 more sources

Insights into the electrophysiology study versus electrocardiographic monitoring trial: Its programmed stimulation protocol may introduce bias when assessing long-term antiarrhythmic drug therapy [PDF]

open access: yes, 1995
Objectives. We hypothesized that if the Electrophysiology Study Versus Electrocardiographic Monitoring (ESVEM) trial programmed stimulation protocol misclassified some drug trials as effective, then the misclassification rate would be proportionally ...
Biblo, Lee A.   +2 more
core   +1 more source

Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats

open access: yesPharmaceutics, 2019
Previous observations demonstrated that cimetidine decreased the clearance of procainamide (PA) and/or N-acetylprocainamide (NAPA; the primary metabolite of PA) resulting in the increased systemic exposure and the decrease of urinary excretion.
Yoo-Seong Jeong   +4 more
doaj   +1 more source

Relation between repolarization and refractoriness in the human ventricle: Cycle length dependence and effect of procainamide [PDF]

open access: yes, 1992
The cycle length dependence of the action potential duration and the effective refractory period of the right ventricular endocardium were investigated in 24 patients undergoing electrophysiologic studies for suspected ventricular tachycardia. The action
Cohen, Todd J.   +3 more
core   +1 more source

Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Application to a Pharmacokinetic Study in Rats

open access: yesPharmaceutics, 2018
A simple, sensitive, and reliable reversed-phase, Ultra-High-Pressure Liquid Chromatography (UHPLC) coupled with a Diode Array Detector (DAD) method for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamide ...
Anusha Balla   +3 more
doaj   +1 more source

Systemic lupus erythematosus (SLE) induced by quinidine [PDF]

open access: yes, 1985
Only two definite cases of quinidine-induced systemic lupus erythematosus (SLE) are reported in the English-language literature. We have treated five patients who had an SLE-like syndrome while receiving quinidine.
Biundo, Joseph   +3 more
core   +1 more source

Effects of Verapamil and Procainamide on Acute Atrial Electrical Remodeling Induced by Short-term Rapid Atrial Pacing in Humans

open access: yesKaohsiung Journal of Medical Sciences, 2007
Atrial electrical remodeling (ER) after spontaneous or pacing-induced atrial fibrillation has been previously described in humans. We investigated atrial ER induced by a 5-minute period of rapid atrial pacing and the pharmacologic effects of verapamil ...
Chih-Sheng Chu   +7 more
doaj   +1 more source

Cyclodextrin potentiometric sensors based on selective recognition sites for procainamide: Comparative and theoretical study

open access: yesOpen Chemistry, 2019
Polyvinyl chloride (PVC) membrane sensors were constructed and developed for the determination of procainamide HCl (PR). Three membrane sensors incorporating α-, β- and γ- cyclodextrin (CD) as ionophores with potassium tetrakis (4-chlorophenyl) borate ...
AlRabiah Haitham   +3 more
doaj   +1 more source

Unmasked by Fever: Diagnosing Brugada Syndrome After Ventricular Fibrillation Arrest

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
A 65-year-old man presented to the emergency department after he was resuscitated from cardiac arrest due to ventricular fibrillation. Coronary angiography demonstrated no evidence of coronary artery disease. Follow-up electrocardiograms (ECGs) were also
Theodore Peng   +3 more
doaj   +1 more source

Design of Intelligent Molecules as Models for Production of New Anti-alzheimer´s Medicines Using Epigenetic Modulation

open access: yesChemical Engineering Transactions, 2019
Alzheimer's disease is a neurodegenerative illness, so far without cure, that affects an increasing number of people around the world. Due to the adverse effects caused by drugs for treating this disease currently in clinical use, it is necessary to ...
Geane Oliveira   +4 more
doaj   +1 more source

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