Results 21 to 30 of about 5,581 (154)

Simultaneous Determination of Procainamide and N-acetylprocainamide in Rat Plasma by Ultra-High-Pressure Liquid Chromatography Coupled with a Diode Array Detector and Its Application to a Pharmacokinetic Study in Rats

open access: yesPharmaceutics, 2018
A simple, sensitive, and reliable reversed-phase, Ultra-High-Pressure Liquid Chromatography (UHPLC) coupled with a Diode Array Detector (DAD) method for the simultaneous determination of Procainamide (PA) and its major metabolite, N-acetylprocainamide ...
Anusha Balla   +3 more
doaj   +1 more source

Unmasked by Fever: Diagnosing Brugada Syndrome After Ventricular Fibrillation Arrest

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
A 65-year-old man presented to the emergency department after he was resuscitated from cardiac arrest due to ventricular fibrillation. Coronary angiography demonstrated no evidence of coronary artery disease. Follow-up electrocardiograms (ECGs) were also
Theodore Peng   +3 more
doaj   +1 more source

Design of Intelligent Molecules as Models for Production of New Anti-alzheimer´s Medicines Using Epigenetic Modulation

open access: yesChemical Engineering Transactions, 2019
Alzheimer's disease is a neurodegenerative illness, so far without cure, that affects an increasing number of people around the world. Due to the adverse effects caused by drugs for treating this disease currently in clinical use, it is necessary to ...
Geane Oliveira   +4 more
doaj   +1 more source

Diagnosis and management of junctional ectopic tachycardia in children

open access: yesAnnals of Pediatric Cardiology, 2021
Junctional ectopic tachycardia (JET) is more common in its postoperative form. A thorough understanding of its etiology, pathophysiology, and management strategies is essential.
Navaneetha Sasikumar   +2 more
doaj   +1 more source

Cyclodextrin potentiometric sensors based on selective recognition sites for procainamide: Comparative and theoretical study

open access: yesOpen Chemistry, 2019
Polyvinyl chloride (PVC) membrane sensors were constructed and developed for the determination of procainamide HCl (PR). Three membrane sensors incorporating α-, β- and γ- cyclodextrin (CD) as ionophores with potassium tetrakis (4-chlorophenyl) borate ...
AlRabiah Haitham   +3 more
doaj   +1 more source

Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals. [PDF]

open access: yesPLoS ONE, 2018
Non-uniform shortening of the action potential duration (APD90) in different myocardial regions upon heart rate acceleration can set abnormal repolarization gradients and promote arrhythmia.
Oleg E Osadchii
doaj   +1 more source

Procainamide, oxprenolol and amiodarone as antidysrhythmic drugs in myocardial infarction.

open access: yesActa Médica Portuguesa, 1980
Using Holter recordings and based on the principle that most of the survivors of acute myocardial infarction who are going to die suddenly after hospital discharge are those who present ventricular premature beats (VPB), the authors have studied the ...
J. L. Tuna   +5 more
doaj   +3 more sources

Epigenetically Altered T Cells Contribute to Lupus Flares

open access: yesCells, 2019
Lupus flares when genetically predisposed people encounter exogenous agents such as infections and sun exposure and drugs such as procainamide and hydralazine, but the mechanisms by which these agents trigger the flares has been unclear. Current evidence
Bruce Richardson
doaj   +1 more source

Effect of voltage-gated sodium channels blockers on motility and viability of human sperm in vitro

open access: yesAsian Pacific Journal of Reproduction, 2018
Objective: To test the effect of voltage-gated sodium channels (VGSCs) blockers on the motility and viability of human sperm in-vitro and to evaluate the tested compounds as potential contact spermicidal.Methods: Sperm samples were obtained from healthy ...
Hammad Ahmad Gakhar   +3 more
doaj   +1 more source

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