Results 31 to 40 of about 5,581 (154)

Aromatic Amines Exert Contrasting Effects on the Anticoagulant Effect of Acetaldehyde upon APTT

open access: yesAdvances in Hematology, 2014
The pharmacological effects of amphetamine, procaine, procainamide, DOPA, isoproterenol, and atenolol upon activated partial thromboplastin time in the absence and presence of acetaldehyde have been investigated.
La'Teese Hall   +2 more
doaj   +1 more source

Wolff-Parkinson-White Syndrome: Electrocardiogram

open access: yesJournal of Education and Teaching in Emergency Medicine, 2016
History of present illness: A 26-year-old male with no significant past medical history presented to the emergency department with palpitations. The patient experienced these symptoms five times before in his life, but they had self-resolved with ...
Brianna Miner   +2 more
doaj   +1 more source

Glucagon‐Like Peptide 1 Receptor Agonists, Sodium‐Glucose Cotransporter 2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

open access: yesArthritis &Rheumatology, EarlyView.
Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter 2 inhibitors (SGLT2i) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear.
Derin Karacabeyli   +4 more
wiley   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou   +14 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

open access: yesPhytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam   +14 more
wiley   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

open access: yesOral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier   +6 more
wiley   +1 more source

Cardiovascular collapse during amiodarone infusion in a hemodynamically compromised child with refractory supraventricular tachycardia

open access: yesAnnals of Pediatric Cardiology, 2015
We describe a 7-week-old female infant who presented with refractory supraventricular tachycardia (SVT). During amiodarone infusion, she developed hypotension and cardiac arrest requiring extracorporeal membrane oxygenation (ECMO) support.
Sunil Saharan, Seshadri Balaji
doaj   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Catheter ablation of recurrent polymorphic tachycardia: Use of sodium channel blockade to organize the tachycardia: A case report

open access: yesIndian Pacing and Electrophysiology Journal, 2015
A 55 year old male presented with recurrent implantable cardioverter defibrillator (ICD) shocks due to polymorphic ventricular tachycardia (PMVT). He had undergone prior catheter ablation for VT three years ago.
Daljeet Kaur Saggu   +4 more
doaj   +1 more source

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