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Using Procalcitonin to Guide Antibiotic Therapy [PDF]
Open Forum Infectious Diseases, 2017 Procalcitonin levels rise in response to systemic inflammation, especially of bacterial origin. Multiple randomized controlled trials have demonstrated that procalcitonin-based algorithms can safely reduce antibiotic use in 2 clinical scenarios.
Chanu Rhee
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Journal of Clinical Pathology, 2015
Procalcitonin (PCT) is the 116 amino acid precursor of the hormone calcitonin, produced by the C cells of the thyroid. Its synthesis is upregulated in bacterial infection and downregulated by viral infection. Consequently, with the increasing development of antibiotic resistance, interest has focused on the ability of this marker to not only diagnose ...
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Procalcitonin (PCT) is the 116 amino acid precursor of the hormone calcitonin, produced by the C cells of the thyroid. Its synthesis is upregulated in bacterial infection and downregulated by viral infection. Consequently, with the increasing development of antibiotic resistance, interest has focused on the ability of this marker to not only diagnose ...
openaire +3 more sources
Procalcitonin for guidance of antibiotic therapy
Expert Review of Anti-Infective Therapy, 2010 Procalcitonin is a surrogate biomarker for estimating the likelihood of a bacterial infection. Procalcitonin-guided initiation and termination of antibiotic therapy is a novel approach utilized to reduce antibiotic overuse.
Philipp Schuetz +2 more
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The usage of procalcitonin in Finland
Acta Anaesthesiologica Scandinavica, 2018BackgroundWe have surveyed the use of procalcitonin (PCT) in Finland with a specific emphasis on intensive care unit (ICU) patients.MethodsThe PCT use was surveyed from all 11 laboratories providing services for all 15 secondary and all five tertiary care hospitals in Finland.
B. Tujula +6 more
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Archives of disease in childhood - Education & practice edition, 2018
Diagnosing bacterial infection in the unwell or febrile child is a common challenge faced by all paediatricians. Despite the advent of novel molecular techniques, there is ongoing need for diagnostic assays with adequate performance and turnaround time to facilitate safe clinical decision-making when bacterial sepsis is suspected, such as whether to ...
Philip, Robinson, Surjo Kiran, De
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Diagnosing bacterial infection in the unwell or febrile child is a common challenge faced by all paediatricians. Despite the advent of novel molecular techniques, there is ongoing need for diagnostic assays with adequate performance and turnaround time to facilitate safe clinical decision-making when bacterial sepsis is suspected, such as whether to ...
Philip, Robinson, Surjo Kiran, De
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Procalcitonin in hantavirus infections
Scandinavian Journal of Clinical and Laboratory Investigation, 2011In hantavirus infections levels of serum leukocytes or C-reactive protein are usually elevated to levels found in serious bacterial infections. However, procalcitonin in patients infected with hantavirus has not yet been discussed in the literature.
Matjaž, Jereb +5 more
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Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2010
This article reviews the production, metabolism, and clinical application of procalcitonin (PCT). PCT is a useful indicator to differentiate bacterial infection and virus infection. Also, it can be used to determine the infection severity and prognosis.
Xi, Wu, Xue-Zhong, Yu
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This article reviews the production, metabolism, and clinical application of procalcitonin (PCT). PCT is a useful indicator to differentiate bacterial infection and virus infection. Also, it can be used to determine the infection severity and prognosis.
Xi, Wu, Xue-Zhong, Yu
openaire +1 more source