Results 51 to 60 of about 10,334 (295)

Java problem-based learning [PDF]

Vojnotehnički Glasnik, 2012
The paper describes the self-directed problem-based learning system (PBL) named Java PBL. The expert module is the kernel of Java PBL. It involves a specific domain model, a problem generator and a solution generator.
Goran P, Šimić
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

ECOLE: a pedagogical environment for non procedural languages

Journal of Computer Science and Technology, 2007
The work described in this paper is related to three areas in the programming world : logic, functional and object programming. The main objective is essentially pedagogical since it is question here to make a synthesis on non procedural languages.
D. E. Zegour, W. K. Hidouci
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Object-Oriented Programming in Bulgarian Universities' Informatics and Computer Science Curricula

Informatics in Education, 2008
Teaching object-oriented programming (OOP) is related to many difficulties. There is no single view on their causes among the university teachers. The results of applying various methods of teaching - with early or late introduction of the objects, are ...
Ivaylo DONCHEV, Emilia TODOROVA
doaj   +1 more source

Procedural education for cancer-related pain in Pain Medicine fellowships: a national program survey [PDF]

, 2023
Alex Woodrow, Masaru Teramoto, Mrinal Thapliyal, Sandy Christiansen   +3 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Research on the practice of collaborative teaching mode between python programming course and ideological and political education [PDF]

ITM Web of Conferences
In response to the problem that ideological and political education cannot be well integrated into programming courses, an exploration was conducted on the ideological and political education teaching mode of the "Python Programming" course. Firstly, the
Gu Cuihong, Wang Mengxia, Wang Qun
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Analysis of suitable languages to teach Procedural Programming at the Universidad Nacional del Noroeste de la provincia de Buenos Aires

Journal of Computer Science and Technology, 2013
Based on the need to update the language and tools used to teach Procedural Programming during the first year of computer science careers, a cross descriptive research was conducted by assessing different programming languages.
Germán Leandro Osella Massa, Claudia Cecilia Russo, Mónica Sarobe, Sabrina Pompei   +3 more
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