Results 51 to 60 of about 10,219 (294)

An Experimental Study to Evaluate the Impact of the Programming Paradigm in the Testing Activity

CLEI Electronic Journal, 2012
Several techniques and criteria are available to help conducting testing activity. The choice for one of them depends on different aspects, such as the time restrictions, ef- fectiveness of the testing criteria or the features of the program under test ...
Simone de Rocio Senger de Souza, Marllos Paiva Prado, Ellen Francine Barbosa, José Carlos Maldonado   +3 more
doaj   +1 more source

Java problem-based learning [PDF]

Vojnotehnički Glasnik, 2012
The paper describes the self-directed problem-based learning system (PBL) named Java PBL. The expert module is the kernel of Java PBL. It involves a specific domain model, a problem generator and a solution generator.
Goran P, Šimić
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

ECOLE: a pedagogical environment for non procedural languages

Journal of Computer Science and Technology, 2007
The work described in this paper is related to three areas in the programming world : logic, functional and object programming. The main objective is essentially pedagogical since it is question here to make a synthesis on non procedural languages.
D. E. Zegour, W. K. Hidouci
doaj  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Object-Oriented Programming in Bulgarian Universities' Informatics and Computer Science Curricula

Informatics in Education, 2008
Teaching object-oriented programming (OOP) is related to many difficulties. There is no single view on their causes among the university teachers. The results of applying various methods of teaching - with early or late introduction of the objects, are ...
Ivaylo DONCHEV, Emilia TODOROVA
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Research on the practice of collaborative teaching mode between python programming course and ideological and political education [PDF]

ITM Web of Conferences
In response to the problem that ideological and political education cannot be well integrated into programming courses, an exploration was conducted on the ideological and political education teaching mode of the "Python Programming" course. Firstly, the
Gu Cuihong, Wang Mengxia, Wang Qun
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Analysis of suitable languages to teach Procedural Programming at the Universidad Nacional del Noroeste de la provincia de Buenos Aires

Journal of Computer Science and Technology, 2013
Based on the need to update the language and tools used to teach Procedural Programming during the first year of computer science careers, a cross descriptive research was conducted by assessing different programming languages.
Germán Leandro Osella Massa, Claudia Cecilia Russo, Mónica Sarobe, Sabrina Pompei   +3 more
doaj