Results 61 to 70 of about 7,411,622 (289)
Education SciencesGraphs are a conceptually demanding yet foundational component of school mathematics, yet their teaching is often shaped by procedural routines that can obscure weak conceptual understanding.
Rosina Nkadi Ngoako +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Procedural Fairness and the Institutional Dynamic: Where We Are and Where We Should Be Going
, 2017 The chapters in this volume have sought to provide a better understanding of procedural fairness within the international system. Our aims have been restrained given that the research agenda here is new: we have not sought to offer a “universal model” of
Sarvarian, A, Baker, RB
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Indonesian Journal of Science and Mathematics EducationThis study employed a sequential explanatory mixed-methods design to assess students' procedural knowledge in linear programming using the simplex method through quantitative tests, qualitative interviews, and Focus Group Discussions (FGD). The objective
Louie Resti Sandoval Rellon +1 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Safety and efficiency of procedural sedation and analgesia (PSA) conducted by medical officers in a level one hospital in Cape Town [PDF]
, 2011 Objectives: This study aimed to research efficacy and safety of procedural sedation and analgesia (PSA) administered by medical officers (MOs), without formal anaesthetic training, in a South African district hospital.
Wenzel-Smith, Gisela
core +1 more source
Civil claim in criminal proceedings: conceptual approaches to understanding essence
Архів кримінології та судових наукThe article is devoted to the issue of compensation for damage caused by a criminal offense by filing a civil claim in criminal proceedings, which is relevant for modern science of criminal procedure.
Stanislav Moseiko
doaj +1 more source