Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Relaxation and metastability in a local search procedure for the random satisfiability problem [PDF]
Guilhem Semerjian, Rémi Monasson
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The role of the prosthetic axilloaxillary loop access as a tertiary arteriovenous access procedure [PDF]
Thomas W. Kendall +5 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
New procedure for qualification of structured light 3D scanners using an optical feature-based gauge
Susana Martínez-Pellitero +3 more
openalex +2 more sources
Evaluation of Drug Susceptibility of Microorganisms in Odontogenic Inflammations and Dental Surgery Procedures Performed on an Outpatient Basis [PDF]
Mateusz Bogacz +7 more
openalex +1 more source
National Student Survey 2020: Procedures for investigating allegations of inappropriate influence on survey results [PDF]
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PROPOSED PROCEDURE FOR OPTIMAL MAINTENANCE SCHEDULING UNDER EMERGENT FAILURES
Abbas Al‐Refaie +2 more
openalex +2 more sources

