Results 221 to 230 of about 9,026,347 (309)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Penalized eigenvalue block averaging: Extension to nested model comparison and Monte Carlo evaluations. [PDF]
Foldnes N, Grønneberg S, Moss J.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Office- vs Hospital-Based Cardiac Imaging Among Part B Medicare Beneficiaries for Evaluating Coronary Artery Disease. [PDF]
Sayed A +4 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Fluoroscopic radiation exposure during spinal cord stimulation procedures: A systematic review and meta-analysis. [PDF]
Jacques CL +6 more
europepmc +1 more source

