Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Opportunities to Improve Nutrition for Patients in Hospital After Discharge From an Intensive Care Unit: A Human Factors Analysis. [PDF]
Vollam S +5 more
europepmc +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Process-outcome effects in psychotherapy research: an umbrella systematic review and meta-analysis. [PDF]
Gómez Penedo JM, Flückiger C.
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Designing Meaningful Engagement for Older Adults: An Evaluation of Participation in a Five-Day Co-Design Sprint. [PDF]
Nordin S +5 more
europepmc +1 more source
The analytic hierarchy process—what it is and how it is used
R. Saaty
semanticscholar +1 more source
Impossibility of distributed consensus with one faulty process
M. Fischer, N. Lynch, M. Paterson
semanticscholar +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Design, optimization and controllability analysis of an improved sulfur recovery unit based on SuperClaus process. [PDF]
Kazemi T, Eslamloueyan R.
europepmc +1 more source

