Results 111 to 120 of about 1,889,013 (289)

Systematization of Methods and Modern Technologies of Interrelations Between Banks and Clients Management in Ukraine [PDF]

, 2016
Interrelations with clients are the basis of banking system functioning. But in the process of attracting new customers banks should pay attention to avoiding high credit risk and money laundering risk.
Kolodiziev, O. (Oleh), Kotsiuba, O. (Olena)   +1 more
core  

Process Analytical Technologies in Biopharmaceutical Process Development [PDF]

Journal of Chemical Technology & Biotechnology, 2015
Rathore, Anurag S., Gernaey, Krist V., Calado, Cecília R. C., Yoon, Seongkyu   +3 more
openaire   +2 more sources

Hyperspectral Imaging For Process Analytical Technology

, 2011
Hyperspectral Imaging (HI) is a valuable tool for online-analysis and control of production processes. HI is an emerging platform technology that integrates spectroscopy and imaging to gain both spectral and spatial information from a sample. The combination with Multivariate Data Analysis (MVA) permits extraction of the relevant information.
Ostertag, Edwin, Kessler, Rudolf W.
openaire   +2 more sources

A Bioreactor-Based Yellow Fever Virus-like Particle Production Process with Integrated Process Analytical Technology Based on Transient Transfection. [PDF]

Viruses, 2023
Dekevic G, Tertel T, Tasto L, Schmidt D, Giebel B, Czermak P, Salzig D.   +6 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

On the Use of Temperature Measurements as a Process Analytical Technology (PAT) for the Monitoring of a Pharmaceutical Freeze-Drying Process. [PDF]

Pharmaceutics, 2023
Vallan A, Fissore D, Pisano R, Barresi AA.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Machine learning and metabolic modelling assisted implementation of a novel process analytical technology in cell and gene therapy manufacturing. [PDF]

Sci Rep, 2023
Williams T, Kalinka K, Sanches R, Blanchard-Emmerson G, Watts S, Davies L, Knevelman C, McCloskey L, Jones P, Mitrophanous K, Miskin J, Dikicioglu D.   +11 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Construction of high‐loading WO3‐x sub‐nanometer clusters via orderly‐anchored top–down strategy boost acidic hydrogen evolution

EcoEnergy
Exploring a simple, rapid, and scalable synthesis method for the synthesis of high loading nonprecious metal sub‐nanometer clusters (SNCs) electrocatalysts is one of the most promising endeavors today.
Di Wu, Haoyang Du, Ziyi Liu, G. A. Bagliu, Jianping Lai, Lei Wang   +5 more
doaj   +1 more source