Results 111 to 120 of about 2,095,688 (302)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
ModellingMexico City’s Metro Line 7 is a critical north–south artery within one of the world’s largest metro systems, yet it suffers from persistent operational inefficiencies, including chronic overcrowding and extended passenger travel times.
Elias Heriberto Arias Nava +2 more
doaj +1 more source
Capability studies, helpful tools in process quality improvement
MATEC Web of Conferences, 2017 Ability of processes to meet customer’quality requirements has become essential for providing competitive advantages such as cost savings, reducing the number of nonconfoming products or increasing customer satisfaction.
Simion Carmen
doaj +1 more source
A general multivariate latent growth model with applications in student careers Data warehouses
, 2009 The evaluation of the formative process in the University system has been assuming an ever increasing importance in the European countries. Within this context the analysis of student performance and capabilities plays a fundamental role. In this work we
Bartholomew D. J. +6 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in Applied Mathematics and StatisticsProcess capability analysis is the statistical evaluation of process capability to examine how well it meets or exceeds the customers satisfaction. In present work, we are intended to evaluate two critical metrics for process quality assessment, Cpy and ...
Tahira Kanwal +3 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Shape optimization of three-dimensional stamped and solid automotive components [PDF]
The shape optimization of realistic, 3-D automotive components is discussed. The integration of the major parts of the total process: modeling, mesh generation, finite element and sensitivity analysis, and optimization are stressed.
Bennett, J. A. +2 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A study of sample entropy towards process capability [PDF]
Master of ScienceIndustrial & Manufacturing Systems EngineeringShing I. ChangThe process capability is a measurable property of a process related to the specification of a product.
Zhang, Zheng
core