Results 121 to 130 of about 588,383 (305)

Multivariate process capability using principal component analysis in the presence of measurement errors

open access: yes, 2011
Multivariate process capability indices, Principal components analysis, Measurement errors, Gauge Study, MANOVA,
Michele Scagliarini   +1 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A capability maturity approach for construction process improvement: use of case studies approach

open access: yes
During the recent past, the effectiveness of process improvement strategies and the role of information technology have been discussed as a mechanism of achieving the performance improvements within the UK construction industry. However there are visible
Amaratunga, Dilanthi   +2 more
core  

Measuring Regional Innovative Capability [PDF]

open access: yes
Regional innovation environment has experienced remarkable changes in the recent decades. Innovativeness at regional level is seen as a consequence of networked co-operation in a regional innovation system, which sets demands for new kinds of regional ...
Vesa Harmaakorpi, Tomi Tura
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A low volume production process capability analysis

open access: yes, 2009
Statistical Process Control (SPC) and Process Capability Indices (PCI) are used extensively within manufacturing and service environments. This paper reports the results of a statistical quality improvement programme when applied to a low volume, high ...
Chang J Wang (16155056)   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

From capability to concept: Fusion of systems analysis techniques for derivation of future [PDF]

open access: yes, 2007
The intent of this thesis is to define a set of processes for use within UK Government dismounted soldier systems research that will provide stakeholders with auditable and traceable information to understand gaps in military capability and justify ...
Sparks, Emma S.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Measuring the Capability to Raise Revenue Process and Output Dimensions and Their Application to the Zambia Revenue Authority [PDF]

open access: yes
The worldwide diffusion of the good governance agenda and new public management has triggered a renewed focus on state capability and, more specifically, on the capability to raise revenue in developing countries.
Christian von Soest
core  

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