Results 101 to 110 of about 588,383 (305)

Process Capability Evaluation Using Capability Indices as a Part of Statistical Process Control

Mathematics
This study aims to highlight the importance of a systematic approach to process capability assessment and the importance of following a sequence of steps. Statistical process control provides several different ways of assessing process capability.
Marta Benková, Dagmar Bednárová, Gabriela Bogdanovská   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Intervalos de confianza para los índices de capacidad Cpm y Cpmk en procesos estacionarios gaussianos Confidence Intervals for the Capability Indices Cpm and Cpmk in Stationary Gaussian Processes

Revista Colombiana de Estadística, 2006
Los índices de capacidad suministran una medida numérica del ajuste que tiene un proceso a unos límites de especificación preestablecidos. Los procedimientos existentes para construir intervalos de confianza para los índices de capacidad Cpm y Cpmk en ...
RUBEN DARÍO GUEVARA, JOSÉ ALBERTO VARGAS   +1 more
doaj  

Capability studies, helpful tools in process quality improvement

MATEC Web of Conferences, 2017
Ability of processes to meet customer’quality requirements has become essential for providing competitive advantages such as cost savings, reducing the number of nonconfoming products or increasing customer satisfaction.
Simion Carmen
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A Data-Driven Discrete-Event Simulation for Assessing Passenger Dynamics and Bottlenecks in Mexico City Metro Line 7

Modelling
Mexico City’s Metro Line 7 is a critical north–south artery within one of the world’s largest metro systems, yet it suffers from persistent operational inefficiencies, including chronic overcrowding and extended passenger travel times.
Elias Heriberto Arias Nava, Brendan Patrick Sullivan, Luis A. Moncayo-Martinez   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Assessing Multivariate Process Capability in the Presence of Measurements Errors

, 2010
Gauge measurement error is often an important source of variability in manufacturing applications. The aim of this work is to study the effect of multivariate measurement errors on multivariate capability indices computed using the principal component ...
SCAGLIARINI, MICHELE
core  

Bootstrap confidence intervals of process capability indices Cpy and CNpmk using different methods of estimation for Frechet distribution

Frontiers in Applied Mathematics and Statistics
Process capability analysis is the statistical evaluation of process capability to examine how well it meets or exceeds the customers satisfaction. In present work, we are intended to evaluate two critical metrics for process quality assessment, Cpy and ...
Tahira Kanwal, Kamran Abbas, Mehwish Zaman, Zamir Hussain   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source