Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Identification of barriers and enablers to rapid diagnosis along the paediatric stroke chain of recovery using Value-Focused Process Engineering. [PDF]
Mackay MT +7 more
europepmc +1 more source
Sustaining competencies and employability: A fishbone model for engineering education to fit the processes of life [PDF]
Jay Somasundaram +2 more
openalex
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Superior protein titers in half the fermentation time: Promoter and process engineering for the glucose-regulated GTH1 promoter of Pichia pastoris. [PDF]
Prielhofer R +6 more
europepmc +1 more source
Contributions to Statistical Signal Processing with Applications in Biomedical Engineering
Quang Thang Nguyen
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Problems on scientific and methodical maintenance of development and operation of heat-protective coatings for heat-stressed elements of space-rocket engineering. I. Mathematical simulation of processes of the destruction of heat-protective materials [PDF]
В. И. Тимошенко, G. A. Frolov
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Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

