Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
2 Planning and running more rigorous PDSA cycles
BMJ Open Quality, 2023 Lloyd Provost +4 more
doaj +1 more source
Yalın Altı Sigma Metodu ve Bankacılık Sektöründe Uygulanması
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2020 Yalın Altı Sigma, süreçlerde iyileşme, daha kaliteli ürün veya hizmet üretme, daha verimli ve etkili iş modelleri sağlama alanlarında maliyetleri düşürmeyi, israfları mümkün olabildiğince azaltarak, müşteri odağı olmayı hedef alır.
Ülkü Rana Günday +1 more
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Promoting Administrative and Financial Processes of Management and Medical Informatics School of Tabriz University of Medical Sciences by Action Research Methodology [PDF]
Taṣvīr-i salāmat, 2018 Background and Objectives: Administrative and financial affairs are one of the most important activities in any organization. Determining the processes related to these affairs is necessary.
Yalda Mousa Zadeh +4 more
doaj
Hospital Survey on Culture of Transitions in Patient Care at a Community Hospital
Nursing & Health Sciences Research Journal, 2021 Background: Delays in patient transitions of care are complex and, therefore, a reductionist model of improvement is not likely to produce sustainable results.
Gwendolyn Burley +3 more
doaj
FREE SEARCH – A NOVEL HEURISTIC METHOD [PDF]
, 2003 Key words to describe the work: Evolutionary computing, Artificial Intelligence, Free Search. Key Results: Inspired from the nature new population-based algorithm applied to numerical optimisation. How does the work advance the state-of-the-art?: Novel
Littlefair, Guy, Penev, Kalin
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source