Results 131 to 140 of about 14,248,688 (303)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Quality Improvement Division Operations Plan 2018
, 2018 This is the Operational Plan for the Quality Improvement Division (QID) for 2018 and builds on the work done since 2015 to enable the HSE develop and implement a quality improvement agenda and capability across all levels of the ...
Quality Improvement Division
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Influence of the autochthonous cellulolytic bacteria on the domestic compost process improvement. [PDF]
BioTechnologia (Pozn), 2023 Ćwiertniewicz-Wojciechowska M +3 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
National Quality Improvement Team Annual Report 2017
, 2018 This report is a high level overview of work completed by the National Quality Improvement Team (formerly known as the Quality Improvement Division) in 2018.
National Quality Improvement Team
core
Implementation of SEEK in a Children's Advocacy Center: A Process Improvement Initiative. [PDF]
Pediatr Qual Saf, 2022 Letson MM +5 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Software process improvement: assessments for small software firms
, 2010 As software becomes increasingly important to all aspects of industry, there is a need to encourage practitioners to adopt best practice so as to improve the quality of the processes in use, and therefore achieve targets relating to time, budget and ...
Cater-Steel, Aileen
core +1 more source
Optimizing Patient-Reported Outcome Collection and Documentation in Medical Music Therapy: Process-Improvement Study. [PDF]
JMIR Hum Factors, 2023 Rodgers-Melnick SN +3 more
europepmc +1 more source