Results 131 to 140 of about 28,750,719 (342)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Proposal for control process improvement [PDF]
, 2015 Obsahem této práce je analýza a následné zlepšení procesu na pracovišti vstupní kontroly ve firmě GEAC. Zlepšení je provedeno převážně v evidenci záznamů a analýze naměřených dat.
Hončariv Radim
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Kolb Meets Quality: Applying Learning Theory to a Process Improvement and Safety Curriculum. [PDF]
ATS Sch, 2023 Lee MM, Kumar SI.
europepmc +1 more source
SPICE 3: Facilitating organisational process improvement through good practice sharing [PDF]
This paper describes the latest iteration of the SPICE research. SPICE 3 explains the process maturity framework to address the level III of the SPICE model.
Amaratunga, Dilanthi +4 more
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Rosenberg's "Learning by Using" and Technology Diffusion [PDF]
This paper formulates Rosenberg's (1982) "learning by using" as a stochastic process. The producer of machines learns from the experience of users. Due to this learning, the quality of machines improves over time.
Toshihiko Mukoyama
core
Western Baptist Hospital: Problem-Solving With Pneumonia Care Performance Improvement Teams [PDF]
, 2010 Describes successful strategies for strengthening pneumonia care, including multidisciplinary performance improvement teams, process improvements built into staff routines, peer collaboratives, standard order sets, and feedback through concurrent ...
Aimee Lashbrook
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source